Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27873238 | 0.75 | TRIM24 (0.33) | — | |
| SCHEMBL27856631 | 0.73 | PDE2A (0.33) | PDE2A | |
| SCHEMBL6873324 | 0.71 | IDO1 (0.40) | PDE2AEPHX2 | |
| SCHEMBL1274766 | 0.71 | NR4A2 (0.41) | PDE2AEPHX2 | |
| SCHEMBL27876954 | 0.71 | GPR84 (0.45) | — | |
| SCHEMBL6871164 | 0.70 | MAPK1 (0.39) | PDE2AEPHX2 | |
| SCHEMBL27876972 | 0.68 | GPR84 (0.45) | — | |
| SCHEMBL27873283 | 0.66 | PDE2A (0.34) | PDE2AEPHX2 | |
| SCHEMBL29952514 | 0.63 | ERN1 (0.40) | — | |
| SCHEMBL2053177 | 0.61 | PDE2A (0.36) | PDE2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102470132-B | Disubstituted [4-(5-aminomethyl-phenyl)-piperidin-1-yl]-1h-indol-3-yl]-methanones | SANOFI SA | 2013-11-06 | — | — | CN | disclosed |
| CN-102470132-A | Disubstituted [4-(5-aminomethyl-phenyl)-piperidin-1-yl]-1h-indol-3-yl]-methanones | SANOFI AVENTIS | 2012-05-23 | — | — | CN | disclosed |