Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28798411 | 0.82 | ATM (0.68) | EPHX1ATMRAB9AKMT2AMAPT | |
| SCHEMBL8605647 | 0.80 | EPHX1 (0.52) | EPHX1ATMRAB9AKMT2ASHMT2 | |
| SCHEMBL8636134 | 0.80 | EPHX1 (0.52) | EPHX1ATMRAB9AKMT2ASHMT2 | |
| SCHEMBL8603355 | 0.80 | EPHX1 (0.52) | EPHX1ATMRAB9AKMT2ASHMT2 | |
| SCHEMBL8601811 | 0.80 | EPHX1 (0.52) | EPHX1ATMRAB9AKMT2ASHMT2 | |
| SCHEMBL7765488 | 0.80 | EPHX1 (0.54) | EPHX1ATMRAB9AKMT2ASHMT2 | |
| SCHEMBL7767326 | 0.80 | EPHX1 (0.54) | EPHX1ATMRAB9AKMT2ASHMT2 | |
| SCHEMBL7765484 | 0.80 | EPHX1 (0.54) | EPHX1ATMRAB9AKMT2ASHMT2 | |
| SCHEMBL7767336 | 0.80 | EPHX1 (0.54) | EPHX1ATMRAB9AKMT2ASHMT2 | |
| SCHEMBL7767340 | 0.80 | EPHX1 (0.54) | EPHX1ATMRAB9AKMT2ASHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102471339-A | Pyrrolopyridine inhibitors of kinases | ABBOTT LAB | 2012-05-23 | — | — | CN | claimed |
| CN-102471339-A | Pyrrolopyridine inhibitors of kinases | ABBOTT LAB | 2012-05-23 | — | — | CN | disclosed |