Cyanate

Cyanate

SCHEMBL27874992

CC(=O)c1ccc(S)cc1.N#CO

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.45
HPGD P15428 4/20 0.45
RAB9A P51151 3/20 0.45
KMT2A Q03164 2/20 0.45
LMNA P02545 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
ALDH1A1 P00352 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.43
HSD17B1 P14061 1/20 0.43
PGR P06401 1/20 0.42
MAPK1 P28482 2/20 0.41
NOS3 P29474 2/20 0.41
NOS1 P29475 2/20 0.41
MEN1 O00255 1/20 0.41
NPC1 O15118 2/20 0.39
STAT3 P40763 1/20 0.39
STAT1 P42224 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
GAA P10253 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL487360 0.89 MAPT (0.54) MAPTHPGDRAB9AKMT2ALMNA
Methane SCHEMBL8806303 0.86 MAPT (0.52) MAPTHPGDRAB9AKMT2ALMNA
SCHEMBL6517451 0.86 MAPT (0.52) MAPTHPGDRAB9AKMT2ALMNA
SCHEMBL6511474 0.86 MAPT (0.52) MAPTHPGDRAB9AKMT2ALMNA
Benzene SCHEMBL28493451 0.84 MAPT (0.60) MAPTHPGDRAB9AKMT2ALMNA
Acetic Acid SCHEMBL9711112 0.84 MAPT (0.54) MAPTHPGDRAB9AKMT2ALMNA
SCHEMBL11162701 0.82 HSD17B1 (0.64) MAPTHPGDRAB9AKMT2ALMNA
Acetophenone SCHEMBL28878306 0.77 MAPT (0.58) MAPTHPGDRAB9AKMT2ALMNA
SCHEMBL12141690 0.77 HPGD (0.79) MAPTHPGDRAB9AKMT2ALMNA
SCHEMBL12141679 0.77 HPGD (0.79) MAPTHPGDRAB9AKMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102526997-A Golf ball SRI SPORTS LTD 2012-07-04 CN disclosed
CN-102526995-A Golf ball SRI SPORTS LTD 2012-07-04 CN disclosed
CN-102485294-A Golf ball SRI SPORTS LTD 2012-06-06 CN disclosed