SCHEMBL2787828

SCHEMBL2787828

Cc1ccc(S(=O)(=O)OC2CC(C)(C)NC(C)(C)C2)cc1

nearest known ligand 0.49

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 2/20 0.49
CYP1A2 P05177 1/20 0.43
KMT2A Q03164 3/20 0.41
MEN1 O00255 1/20 0.41
GAA P10253 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
CYP3A4 P08684 1/20 0.37
CYP2C19 P33261 1/20 0.37
TSHR P16473 1/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11053573 0.86 GAA (0.51) KMT2AMEN1GAATSHRMAPT
SCHEMBL15898087 0.84 CYP2D6 (0.49) CYP2D6CYP1A2KMT2AGAASMN1; SMN2
SCHEMBL26985372 0.83 CYP2D6 (0.48) CYP2D6CYP1A2KMT2AGAASMN1; SMN2
SCHEMBL21761015 0.83 CYP2D6 (0.54) CYP2D6CYP1A2KMT2AMEN1GAA
SCHEMBL28909487 0.83 CYP2D6 (0.54) CYP2D6CYP1A2KMT2AMEN1GAA
SCHEMBL21571675 0.81 GAA (0.43) KMT2AMEN1GAASMN1; SMN2TSHR
SCHEMBL18047845 0.81 CYP2D6 (0.51) CYP2D6CYP1A2KMT2AGAASMN1; SMN2
SCHEMBL19712291 0.80 CYP2D6 (0.51) CYP2D6CYP1A2KMT2AGAASMN1; SMN2
SCHEMBL11003574 0.80 CYP2D6 (0.55) CYP2D6CYP1A2KMT2AGAASMN1; SMN2
SCHEMBL11009164 0.80 CYP2D6 (0.48) CYP2D6CYP1A2KMT2AGAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100229944-A1 ENCAPSULATING MATERIAL FOR SOLAR CELL DU PONT-MITSUI POLYCHEMICALS CO., LTD. (JP) 2010-09-16 US disclosed
EP-1990840-A1 SOLAR BATTERY SEALING MATERIAL Du Pont-Mitsui Polychemicals Co., Ltd. (JP) 2008-11-12 EP disclosed
WO-2008086436-A1 SPECIFICATION INSULATING SHEET ARTSCAPE, INC. (US) 2008-07-17 WO disclosed
US-20080160299-A1 Heat shielding sheet ACHILLES CORPORATION (JP) 2008-07-03 US disclosed
US-4487870-A BLEND OF ETHYLENE-VINYL ACETATE COPOLYMER WITH PHOTOSTABILIZER EXXON RESEARCH & ENGINEERING CO. (US) 1984-12-11 US disclosed
US-4038218-A SPRAY DRYING KAO SOAP CO., LTD. (JA) 1977-07-26 US disclosed