SCHEMBL28909487

SCHEMBL28909487

Cc1ccc(S(=O)(=O)OC2CC(C)(O)C2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 2/20 0.54
CYP1A2 P05177 1/20 0.44
GAA P10253 2/20 0.42
KMT2A Q03164 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
STS P08842 1/20 0.38
CYP3A4 P08684 2/20 0.38
CYP2C19 P33261 2/20 0.38
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
PKM P14618 2/20 0.38
CYP2C9 P11712 1/20 0.38
HSD11B1 P28845 1/20 0.38
MMP1 P03956 1/20 0.37
MMP2 P08253 1/20 0.37
MMP9 P14780 1/20 0.37
MMP8 P22894 1/20 0.37
MMP13 P45452 1/20 0.37
HTT P42858 1/20 0.37
ALDH1A1 P00352 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21761015 1.00 CYP2D6 (0.54) CYP2D6CYP1A2GAAKMT2ASMN1; SMN2
SCHEMBL15262021 0.88 CYP2D6 (0.52) CYP2D6CYP1A2KMT2ASMN1; SMN2STS
SCHEMBL23585379 0.86 CYP2D6 (0.50) CYP2D6CYP1A2KMT2ASMN1; SMN2STS
SCHEMBL26911802 0.84 CYP2D6 (0.58) CYP2D6CYP1A2GAAKMT2ASMN1; SMN2
SCHEMBL20595253 0.84 CYP2D6 (0.58) CYP2D6CYP1A2GAAKMT2ASMN1; SMN2
SCHEMBL26912003 0.84 CYP2D6 (0.58) CYP2D6CYP1A2GAAKMT2ASMN1; SMN2
SCHEMBL15898087 0.83 CYP2D6 (0.49) CYP2D6CYP1A2GAAKMT2ASMN1; SMN2
SCHEMBL2787828 0.83 CYP2D6 (0.49) CYP2D6CYP1A2GAAKMT2ASMN1; SMN2
SCHEMBL18047845 0.82 CYP2D6 (0.51) CYP2D6CYP1A2GAAKMT2ASMN1; SMN2
SCHEMBL31362321 0.82 CYP2D6 (0.52) CYP2D6CYP1A2KMT2ASMN1; SMN2STS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115322106-B Synthesis method of trans-3-azido-1-methylcyclobutanol and trans-3-amino-1-methylcyclobutanol 沈阳药科大学 2023-08-15 CN disclosed
CN-115322106-A Synthesis method of trans-3-azido-1-methylcyclobutanol and trans-3-amino-1-methylcyclobutanol 沈阳药科大学 2022-11-11 CN disclosed