Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPY2R | P49146 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27373067 | 0.98 | NPSR1 (0.44) | NPSR1MEN1KMT2AL3MBTL1TSHR | |
| Fluoride SCHEMBL28405683 | 0.95 | NPSR1 (0.43) | NPSR1MEN1KMT2AL3MBTL1TSHR | |
| Hydrochloric Acid SCHEMBL28248836 | 0.95 | NPSR1 (0.43) | NPSR1MEN1KMT2AL3MBTL1TSHR | |
| Bromide SCHEMBL28822033 | 0.93 | NPSR1 (0.43) | NPSR1MEN1KMT2AL3MBTL1ALDH1A1 | |
| Bromide SCHEMBL28602408 | 0.91 | NPSR1 (0.47) | NPSR1MEN1KMT2AL3MBTL1ALDH1A1 | |
| Bromide SCHEMBL29021907 | 0.91 | NPSR1 (0.47) | NPSR1MEN1KMT2AL3MBTL1ALDH1A1 | |
| Bromide SCHEMBL28439716 | 0.91 | NPSR1 (0.47) | NPSR1MEN1KMT2AL3MBTL1ALDH1A1 | |
| Bromide SCHEMBL28380380 | 0.91 | NPSR1 (0.47) | NPSR1MEN1KMT2AL3MBTL1ALDH1A1 | |
| Bromide SCHEMBL28614748 | 0.91 | NPSR1 (0.47) | NPSR1MEN1KMT2AL3MBTL1ALDH1A1 | |
| Bromide SCHEMBL28618528 | 0.91 | NPSR1 (0.47) | NPSR1MEN1KMT2AL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107892308-B | ZSM-5 molecular sieve and preparation method thereof | 太原理工大学 | 2021-07-27 | — | — | CN | claimed |
| CN-119569369-A | Composite liquid cement grinding aid and preparation method thereof | 云南素原新材料有限公司 | 2025-03-07 | — | — | CN | disclosed |
| CN-119463145-A | Polyester resin for indoor powder coating and preparation and application thereof | 新中法高分子材料股份有限公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-114425430-B | Catalytic cracking catalyst | 中国石油化工股份有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-114276485-B | Solvent type high-solid low-viscosity acrylic resin and application thereof in pressure-sensitive adhesive | 东莞澳中新材料科技股份有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-115746313-B | Polyester resin, powder coating and preparation method and application thereof | 擎天材料科技有限公司 | 2024-02-06 | — | — | CN | disclosed |
| CN-114762831-B | Preparation method and preparation system of catalytic cracking auxiliary agent | 中国石油化工股份有限公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-116917234-A | Catalytic cracking agent of phosphorus-containing modified molecular sieve, preparation method and preparation system thereof, and application of catalytic cracking agent | 中国石油化工股份有限公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-114957201-B | Preparation method of low-cyclic byproduct polybutylene succinate polyester | 万华化学集团股份有限公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-114762836-B | Preparation method and preparation system of catalytic cracking catalyst of phosphorus-containing modified MFI structure molecular sieve | 中国石油化工股份有限公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-114425432-B | Cracking catalyst, preparation method and application | 中国石油化工股份有限公司 | 2023-07-11 | — | — | CN | disclosed |
| CN-115746313-A | Polyester resin, powder coating, and preparation method and application thereof | 擎天材料科技有限公司 | 2023-03-07 | — | — | CN | disclosed |
| CN-112457472-B | Low-viscosity bio-based magnolol epoxy resin and preparation method thereof | 广东工业大学 | 2022-10-04 | — | — | CN | disclosed |
| CN-107892308-B | ZSM-5 molecular sieve and preparation method thereof | 太原理工大学 | 2021-07-27 | — | — | CN | disclosed |
| CN-112457472-A | Low-viscosity bio-based magnolol epoxy resin and preparation method thereof | 广东工业大学 | 2021-03-09 | — | — | CN | disclosed |
| CN-112063111-A | Modified epoxy resin composition, high-Tg low-loss laminated copper-clad plate and preparation method thereof | 广德龙泰电子科技有限公司 | 2020-12-11 | — | — | CN | disclosed |
| CN-105190436-A | Infrared-sensitive chromogenic composition, infrared-curable chromogenic composition, lithographic printing plate precursor, and plate formation method | FUJIFILM CORP | 2015-12-23 | — | — | CN | disclosed |
| CN-102781898-B | GPBP inhibition using Q2 peptidomimetics | FIBROSTATIN S L | 2014-12-24 | — | — | CN | disclosed |
| CN-102781898-A | GPBP inhibition using Q2 peptidomimetics | FIBROSTATIN S L | 2012-11-14 | — | — | CN | disclosed |
| CN-102775108-A | Water-permeable paving material and preparation method and application thereof | MIAO GENXI | 2012-11-14 | — | — | CN | disclosed |