Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ERN1 | O75460 | 5/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17919212 | 0.83 | CA1 (0.47) | CA1CA2ALDH1A1L3MBTL1TRIM24 | |
| SCHEMBL29818684 | 0.80 | CA1 (0.44) | CA1CA2ALDH1A1L3MBTL1PRKDC | |
| SCHEMBL17916372 | 0.80 | CA1 (0.44) | CA1CA2ALDH1A1L3MBTL1TRIM24 | |
| SCHEMBL1534505 | 0.78 | PRKDC (0.48) | CA1CA2ALDH1A1L3MBTL1PRKDC | |
| SCHEMBL26853579 | 0.78 | CA1 (0.46) | CA1CA2ALDH1A1L3MBTL1PRKDC | |
| SCHEMBL3345839 | 0.76 | CA1 (0.59) | CA1CA2ALDH1A1L3MBTL1PRKDC | |
| SCHEMBL29729025 | 0.76 | CA1 (0.59) | CA1CA2ALDH1A1L3MBTL1PRKDC | |
| SCHEMBL29818616 | 0.76 | CA1 (0.47) | CA1CA2ALDH1A1L3MBTL1PRKDC | |
| SCHEMBL17919297 | 0.75 | CA1 (0.43) | CA1CA2ALDH1A1L3MBTL1TRIM24 | |
| SCHEMBL7102162 | 0.74 | CA1 (0.59) | CA1CA2GABRA1GABRB2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102766099-B | There is compound and salt, preparation method and the purposes of xanthine oxidase inhibitory activity | SHENYANG PHARMACEUTICAL UNIVERSITY (CN) | 2015-09-23 | — | — | CN | disclosed |
| CN-102766099-A | Compound with xanthine oxidase inhibitory activity as well as salt, preparation methods and application thereof | UNIV SHENYANG PHARMACEUTICAL | 2012-11-07 | — | — | CN | disclosed |