SCHEMBL7102162

SCHEMBL7102162

CCc1cccc(C=O)c1OC

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.59
CA2 P00918 1/20 0.59
SRC P12931 1/20 0.46
ERN1 O75460 3/20 0.46
TLR2 O60603 1/20 0.46
TLR1 Q15399 1/20 0.46
TLR6 Q9Y2C9 1/20 0.46
MCL1 Q07820 1/20 0.41
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
ALDH1A1 P00352 4/20 0.40
LMNA P02545 3/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
MEN1 O00255 1/20 0.39
THRB P10828 1/20 0.39
BLM P54132 1/20 0.39
KMT2A Q03164 1/20 0.39
TDP1 Q9NUW8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10586446 0.85 CA1 (0.56) CA1CA2SRCERN1TLR2
SCHEMBL5223765 0.84 CA1 (0.51) CA1CA2SRCERN1TLR2
Hydrochloric Acid SCHEMBL1443837 0.84 CA1 (0.54) CA1CA2SRCERN1TLR2
SCHEMBL2787203 0.83 CA1 (0.73) CA1CA2SRCERN1TLR2
SCHEMBL16955328 0.83 CA1 (0.44) CA1CA2SRCERN1TLR2
SCHEMBL14999526 0.83 CA1 (0.41) CA1CA2ERN1TLR2TLR1
SCHEMBL27754527 0.83 CA1 (0.44) CA1CA2SRCERN1TLR2
SCHEMBL17919212 0.82 CA1 (0.47) CA1CA2SRCERN1TLR2
SCHEMBL7135448 0.82 CA1 (0.53) CA1CA2SRCERN1TLR2
SCHEMBL31130510 0.82 CA1 (0.53) CA1CA2SRCERN1TLR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109761939-B Substituted aryl methylene type Rubrolide compound and preparation method and application thereof 长江大学 2023-11-24 CN disclosed
EP-1355909-A2 DIHYDROPYRAZOLOPYRIDINE COMPOUNDS AND PHARMACEUTICAL USE THEREOF Mitsubishi Pharma Corporation (JP) 2003-10-29 EP disclosed
WO-2002062795-A2 DIHYDROPYRAZOLOPYRIDINE COMPOUNDS AND PHARMACEUTICAL USE THEREOF MITSUBISHI PHARMA CORPORATION (JP) 2002-08-15 WO disclosed