Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 20/20 | 0.75 |
| ▸ | HCRTR2 | O43614 | 20/20 | 0.75 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1671072 | 0.86 | HCRTR1 (1.00) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL27900616 | 0.80 | HCRTR1 (0.74) | HCRTR1HCRTR2 | |
| SCHEMBL1672522 | 0.80 | HCRTR1 (1.00) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL1671303 | 0.78 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL27900618 | 0.76 | HCRTR1 (0.74) | HCRTR1HCRTR2 | |
| SCHEMBL1671476 | 0.76 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL1671620 | 0.76 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL1671991 | 0.75 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL27883254 | 0.75 | HCRTR1 (0.75) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL6923525 | 0.74 | HCRTR1 (1.00) | HCRTR1HCRTR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102781942-A | Disubstituted octahy-dropyrrolo [3,4-c]pyrroles as orexin receptor modulators | JANSSEN PHARMACEUTICA NV | 2012-11-14 | — | — | CN | claimed |