Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 17/20 | 0.49 |
| ▸ | PSEN2 | P49810 | 17/20 | 0.49 |
| ▸ | APH1B | Q8WW43 | 17/20 | 0.49 |
| ▸ | NCSTN | Q92542 | 17/20 | 0.49 |
| ▸ | APH1A | Q96BI3 | 17/20 | 0.49 |
| ▸ | PSENEN | Q9NZ42 | 17/20 | 0.49 |
| ▸ | CNR2 | P34972 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL278731 | 0.90 | PSEN1 (0.57) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL12379835 | 0.88 | PSEN1 (0.55) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL23772349 | 0.85 | PSEN1 (0.53) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL15576935 | 0.83 | PSEN1 (0.51) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL12379837 | 0.83 | CNR2 (0.55) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL278836 | 0.82 | TP53 (0.55) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL27943816 | 0.82 | CNR2 (0.57) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL5519249 | 0.80 | PSEN1 (0.57) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL11787465 | 0.80 | PSEN1 (0.55) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL11788132 | 0.80 | PSEN1 (0.55) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8134143-B2 | 2,7-carbazolenevinylene derivatives as novel materials in producing organic based electronic devices | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2012-03-13 | — | — | US | disclosed |
| US-20070176163-A1 | 2,7-Carbazolenevinylene derivatives as novel materials in producing organic based electronic devices | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2007-08-02 | — | — | US | disclosed |