Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 16/20 | 0.57 |
| ▸ | PSEN2 | P49810 | 16/20 | 0.57 |
| ▸ | APH1B | Q8WW43 | 16/20 | 0.57 |
| ▸ | NCSTN | Q92542 | 16/20 | 0.57 |
| ▸ | APH1A | Q96BI3 | 16/20 | 0.57 |
| ▸ | PSENEN | Q9NZ42 | 16/20 | 0.57 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.55 |
| ▸ | CNR2 | P34972 | 2/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | RORA | P35398 | 1/20 | 0.50 |
| ▸ | RORC | P51449 | 1/20 | 0.50 |
| ▸ | RORB | Q92753 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28899271 | 0.94 | PTGER4 (0.58) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL279067 | 0.93 | PSEN1 (0.49) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL278612 | 0.93 | PSEN1 (0.49) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL4821945 | 0.92 | PTGER4 (0.66) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL28412652 | 0.92 | PTGER4 (0.66) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL31174405 | 0.92 | PTGER4 (0.66) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL28446594 | 0.92 | PTGER4 (0.66) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL5153575 | 0.92 | PTGER4 (0.66) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL28369278 | 0.92 | PTGER4 (0.66) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL28142613 | 0.92 | PTGER4 (0.66) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070069197-A1 | Monomers, oligomers and polymers of 2-functionalized and 2,7-difunctionalized carbzoles | UNIVERSITE LAVAL (CA) | 2007-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070069197-A1 | Monomers, oligomers and polymers of 2-functionalized and 2,7-difunctionalized carbzoles | TELO2, DNMT1, DDT | PSEN1 4166/4885PSEN2 3936/4885APH1B 2571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.