Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 11/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 6/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.41 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27902092 | 0.82 | MAP4K4 (0.62) | FYNMAP4K4CHEK2KCNH2TGFBR1 | |
| SCHEMBL28051403 | 0.82 | USP7 (0.57) | FYNMAP4K4CHEK2KCNH2 | |
| SCHEMBL28800238 | 0.81 | KCNH2 (0.63) | FYNMAP4K4CHEK2KCNH2TGFBR1 | |
| SCHEMBL27902090 | 0.80 | FYN (0.46) | FYNMAP4K4CHEK2KCNH2TGFBR1 | |
| SCHEMBL2225053 | 0.80 | KCNH2 (0.67) | FYNMAP4K4CHEK2KCNH2 | |
| SCHEMBL27902108 | 0.79 | FYN (0.59) | FYNMAP4K4CHEK2KCNH2 | |
| SCHEMBL27885050 | 0.78 | MAP4K4 (0.60) | FYNMAP4K4CHEK2 | |
| SCHEMBL27885129 | 0.78 | MAP4K4 (0.52) | FYNMAP4K4CHEK2KCNH2 | |
| SCHEMBL27902088 | 0.77 | FYN (0.54) | FYNMAP4K4CHEK2KCNH2 | |
| SCHEMBL27902091 | 0.77 | FYN (0.48) | FYNMAP4K4CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102812006-A | New anti-malarial agents | MEDICINES FOR MALARIA VENTURE MMV | 2012-12-05 | — | — | CN | claimed |
| CN-102812006-A | New anti-malarial agents | MEDICINES FOR MALARIA VENTURE MMV | 2012-12-05 | — | — | CN | disclosed |