Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 2/20 | 0.57 |
| ▸ | FYN | P06241 | 4/20 | 0.55 |
| ▸ | MAP4K4 | O95819 | 12/20 | 0.53 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.50 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.50 |
| ▸ | MINK1 | Q8N4C8 | 2/20 | 0.48 |
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27885119 | 0.93 | USP7 (0.70) | USP7FYNMAP4K4CHEK2MKNK1 | |
| SCHEMBL27885050 | 0.93 | MAP4K4 (0.60) | USP7FYNMAP4K4CHEK2MKNK1 | |
| SCHEMBL27885129 | 0.93 | MAP4K4 (0.52) | USP7FYNMAP4K4CHEK2MKNK1 | |
| SCHEMBL27902097 | 0.91 | FYN (0.53) | USP7FYNMAP4K4CHEK2MKNK1 | |
| SCHEMBL27902105 | 0.90 | USP7 (0.47) | USP7FYNMAP4K4CHEK2MKNK1 | |
| SCHEMBL27885062 | 0.90 | USP7 (0.50) | USP7FYNMAP4K4CHEK2MKNK1 | |
| SCHEMBL27902095 | 0.89 | MAP4K4 (0.62) | USP7FYNMAP4K4CHEK2MKNK1 | |
| SCHEMBL27885054 | 0.89 | MAP4K4 (0.62) | USP7FYNMAP4K4CHEK2MKNK1 | |
| SCHEMBL28051402 | 0.89 | CHEK2 (0.68) | FYNMAP4K4CHEK2MKNK1 | |
| SCHEMBL27902088 | 0.89 | FYN (0.54) | USP7FYNMAP4K4CHEK2MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102812006-B | Novel antimalaria reagent | MMV MEDICINES FOR MALARIA VENTURE (CH) | 2016-01-20 | — | — | CN | claimed |
| CN-102812006-B | Novel antimalaria reagent | MMV MEDICINES FOR MALARIA VENTURE (CH) | 2016-01-20 | — | — | CN | disclosed |