Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28047900 | 0.81 | MEN1 (0.59) | MEN1KMT2AGAAMAPTKDM4E | |
| SCHEMBL27870090 | 0.78 | MEN1 (0.66) | MEN1KMT2AMAPTKDM4EL3MBTL1 | |
| SCHEMBL16210519 | 0.68 | KMT2A (1.00) | MEN1KMT2AGAAMAPTL3MBTL1 | |
| SCHEMBL3276060 | 0.66 | MEN1 (0.63) | MEN1KMT2AGAAMAPTKDM4E | |
| SCHEMBL16226881 | 0.65 | MAPT (0.60) | MEN1KMT2AMAPTKDM4EL3MBTL1 | |
| SCHEMBL3276058 | 0.63 | KMT2A (0.50) | MEN1KMT2AGAAMAPTKDM4E | |
| SCHEMBL15864613 | 0.63 | MAPT (0.62) | MEN1KMT2AMAPTKDM4EL3MBTL1 | |
| SCHEMBL14680498 | 0.62 | MAPT (0.61) | MEN1KMT2AMAPTKDM4EL3MBTL1 | |
| SCHEMBL15676390 | 0.62 | MAPT (0.54) | MEN1KMT2AMAPTKDM4EL3MBTL1 | |
| SCHEMBL10599995 | 0.62 | MEN1 (0.72) | MEN1KMT2AMAPTKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102627593-A | 1,4-dihydroxy-2-formyl-9,10 anthraquinone thiosemicarbazone new compound with anticancer activity and preparation method thereof | UNIV HENAN NORMAL | 2012-08-08 | — | — | CN | disclosed |
| CN-102627593-A | 1,4-dihydroxy-2-formyl-9,10 anthraquinone thiosemicarbazone new compound with anticancer activity and preparation method thereof | UNIV HENAN NORMAL | 2012-08-08 | — | — | CN | disclosed |