Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.64 |
| ▸ | PARP15 | Q460N3 | 4/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.50 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5465598 | 0.78 | RAB9A (0.64) | NPC1RAB9ALMNASMN1; SMN2MEN1 | |
| SCHEMBL22192683 | 0.77 | PARP15 (0.65) | NR1H4PARP15PARP10PARP2NPC1 | |
| SCHEMBL7016979 | 0.77 | PTGIR (0.58) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28487939 | 0.76 | CYP11B1 (0.59) | NPC1RAB9AMEN1KMT2ARXFP1 | |
| SCHEMBL5468876 | 0.74 | TRPV1 (0.60) | NPC1RAB9ALMNASMN1; SMN2MEN1 | |
| SCHEMBL5468404 | 0.74 | NQO2 (0.54) | NPC1RAB9ALMNAMEN1KMT2A | |
| SCHEMBL750529 | 0.74 | KCNK3 (0.59) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL28488053 | 0.73 | MEN1 (0.63) | NPC1RAB9AMEN1KMT2A | |
| SCHEMBL26985992 | 0.73 | NPC1 (0.61) | NPC1RAB9ALMNASMN1; SMN2MEN1 | |
| SCHEMBL26986027 | 0.73 | CYP11B1 (0.55) | NPC1RAB9ALMNASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105254623-A | SUBSTITUTED BENZAMIDES | HOFFMANN LA ROCHE | 2016-01-20 | — | — | CN | disclosed |
| CN-102686563-A | Substituted benzamide derivatives | HOFFMANN LA ROCHE | 2012-09-19 | — | — | CN | disclosed |