Benzene

Benzene

SCHEMBL27888317

O=C(O)c1ccc2ccc3ccc(C(=O)O)nc3c2n1.[Eu].c1ccccc1

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.68
KMT2A Q03164 2/20 0.68
TDP1 Q9NUW8 2/20 0.58
ALOX15 P16050 1/20 0.58
TSHR P16473 1/20 0.58
ACMSD Q8TDX5 1/20 0.58
MGAM O43451 1/20 0.57
MMP2 P08253 4/20 0.53
MEN1 O00255 1/20 0.52
LMNA P02545 1/20 0.52
MAPT P10636 1/20 0.46
RAB9A P51151 1/20 0.46
PIM1 P11309 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL27872024 0.98 KDM4E (0.70) KDM4EKMT2ATDP1ALOX15TSHR
SCHEMBL1088781 0.95 KDM4E (0.67) KDM4EKMT2ATDP1ALOX15TSHR
Hydrochloric Acid SCHEMBL10553456 0.93 KDM4E (0.64) KDM4EKMT2ATDP1ALOX15TSHR
Methyl Alcohol SCHEMBL28609065 0.91 KDM4E (0.62) KDM4EKMT2ATDP1ALOX15TSHR
SCHEMBL18364470 0.85 KDM4E (0.56) KDM4EKMT2ATDP1ALOX15TSHR
SCHEMBL3930639 0.84 KDM4E (0.66) KDM4EKMT2ATDP1ALOX15TSHR
SCHEMBL14610933 0.84 KDM4E (0.60) KDM4EKMT2ATDP1ALOX15TSHR
SCHEMBL29894121 0.83 KDM4E (0.55) KDM4EKMT2ATDP1ALOX15TSHR
SCHEMBL29120624 0.83 RAB9A (0.60) KDM4EKMT2ATDP1ALOX15TSHR
Ammonia Solution, Strong SCHEMBL31590844 0.82 KDM4E (0.64) KDM4EKMT2ATDP1ALOX15TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102676157-A Fluorescent microsphere marker and preparation method thereof TRIPLEX INTERNAT BIOSCIENCES CHINA CO LTD 2012-09-19 CN disclosed