Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27874587 | 0.81 | ALDH1A1 (0.41) | ALDH1A1PKMSOS1KMT2AMITF | |
| SCHEMBL27890898 | 0.80 | ALDH1A1 (0.39) | ALDH1A1PKMSOS1KMT2AMITF | |
| SCHEMBL27890849 | 0.80 | ALDH1A1 (0.42) | ALDH1A1PKMSOS1KMT2AMITF | |
| SCHEMBL3282371 | 0.72 | ALDH1A1 (0.44) | ALDH1A1PKMSOS1KMT2AMITF | |
| SCHEMBL27262043 | 0.69 | ALDH1A1 (0.54) | ALDH1A1PKMSOS1KMT2AMITF | |
| SCHEMBL3466332 | 0.69 | ALDH1A1 (0.46) | ALDH1A1PKMSOS1KMT2AMITF | |
| SCHEMBL27890859 | 0.68 | ALDH1A1 (0.41) | ALDH1A1PKMSOS1KMT2AMITF | |
| SCHEMBL25791997 | 0.68 | ALDH1A1 (0.41) | ALDH1A1PKMSOS1KMT2AMITF | |
| SCHEMBL1227172 | 0.67 | ALDH1A1 (0.44) | ALDH1A1PKMSOS1KMT2AMITF | |
| SCHEMBL30576258 | 0.66 | ALDH1A1 (0.46) | ALDH1A1PKMSOS1KMT2AMITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102741259-A | Nitroimidazooxazine and nitroimidazooxazole analogues and uses thereof | GLOBAL ALLIANCE FOR TB DRUG DEV | 2012-10-17 | — | — | CN | disclosed |