Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.36 |
| ▸ | FPR3 | P25089 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | ACP1 | P24666 | 1/20 | 0.34 |
| ▸ | CCR3 | P51677 | 2/20 | 0.33 |
| ▸ | KHK | P50053 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL28010204 | 0.86 | GBA1 (0.46) | GBA1SLC6A4EP300ITGB3ITGA2B | |
| Tert-Butyl Formate SCHEMBL28566264 | 0.84 | SLC6A4 (0.42) | GBA1SLC6A4KDM1AEP300FPR2 | |
| Tert-Butyl Formate SCHEMBL27819619 | 0.83 | SLC6A4 (0.49) | GBA1SLC6A4EP300FPR2ITGB3 | |
| Tert-Butyl Formate SCHEMBL27819635 | 0.83 | SLC6A4 (0.40) | GBA1SLC6A4ITGB3ITGA2BPIM1 | |
| Tert-Butyl Formate SCHEMBL28795120 | 0.83 | SLC6A4 (0.50) | GBA1SLC6A4ITGB3ITGA2BPIM1 | |
| SCHEMBL578602 | 0.82 | GBA1 (0.66) | GBA1SLC6A4KDM1AEP300FPR3 | |
| Tert-Butyl Formate SCHEMBL27846336 | 0.82 | HTR2C (0.44) | GBA1KDM1AITGB3ITGA2BCCR5 | |
| Tert-Butyl Formate SCHEMBL27798465 | 0.82 | SLC6A4 (0.41) | GBA1SLC6A4EP300TDP1PIM1 | |
| Tert-Butyl Formate SCHEMBL28784348 | 0.81 | KDM1A (0.37) | GBA1SLC6A4KDM1AEP300TDP1 | |
| Tert-Butyl Formate SCHEMBL27950764 | 0.79 | HTR2C (0.44) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102892766-B | Kinase inhibitors and method of treating cancer with same | UNIV HEALTH NETWORK | 2015-05-20 | — | — | CN | disclosed |
| CN-102892766-A | Kinase inhibitors and method of treating cancer with same | UNIV HEALTH NETWORK | 2013-01-23 | — | — | CN | disclosed |