Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.37 |
| ▸ | EP300 | Q09472 | 4/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3051022 | 0.84 | SLC6A4 (0.46) | KDM1AEP300SLC6A4HRH3HRH4 | |
| Tert-Butyl Formate SCHEMBL27891735 | 0.81 | GBA1 (0.46) | KDM1AEP300SLC6A4GBA1TDP1 | |
| Tert-Butyl Formate SCHEMBL28566264 | 0.79 | SLC6A4 (0.42) | KDM1AEP300SLC6A4HRH3HRH4 | |
| Tert-Butyl Formate SCHEMBL27993861 | 0.79 | KDM5C (0.38) | SLC6A4HRH3ALDH1A1 | |
| Tert-Butyl Formate SCHEMBL27841082 | 0.74 | CPB1 (0.40) | KDM1AEP300SLC6A4HRH3HRH4 | |
| Tert-Butyl Formate SCHEMBL27722913 | 0.73 | TDP1 (0.50) | KDM1AGBA1TDP1 | |
| SCHEMBL27961892 | 0.72 | KDM1A (0.32) | KDM1AEP300NPC1ALDH1A1RAB9A | |
| Tert-Butyl Formate SCHEMBL28016851 | 0.72 | TDP1 (0.45) | KDM1AEP300GBA1TDP1 | |
| Tert-Butyl Formate SCHEMBL27950764 | 0.71 | HTR2C (0.44) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27702406 | 0.71 | TDP1 (0.48) | KDM1ASLC6A4GBA1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101795567-A | New heteocyclic H3 antagonists | HIGH POINT PHARMACEUTICALS LLC | 2010-08-04 | — | — | CN | disclosed |