Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27891749 | 0.94 | KMT2A (0.42) | MEN1KMT2AATMMAPK1CYP19A1 | |
| SCHEMBL27891766 | 0.89 | ABCB1 (0.46) | ABCB1KMT2ASLC6A4SLC6A2HRH1 | |
| SCHEMBL27908738 | 0.84 | ABCB1 (0.42) | ABCB1KMT2ASLC6A4SLC6A2HRH1 | |
| SCHEMBL27891786 | 0.84 | ABCB1 (0.42) | ABCB1SLC6A4SLC6A2HRH1SMN1; SMN2 | |
| SCHEMBL27891783 | 0.81 | CYP19A1 (0.45) | ABCB1MEN1KMT2ASLC6A4SLC6A2 | |
| SCHEMBL27908719 | 0.81 | MEN1 (0.42) | ABCB1MEN1KMT2ASLC6A4SLC6A2 | |
| SCHEMBL27891745 | 0.77 | RCE1 (0.42) | ABCB1KMT2ASLC6A4SLC6A2HRH1 | |
| SCHEMBL27908731 | 0.77 | MCL1 (0.49) | MEN1KMT2ASLC6A4SLC6A2HRH1 | |
| SCHEMBL27891723 | 0.77 | KDM4E (0.43) | MEN1KMT2AATMMAPK1CYP19A1 | |
| SCHEMBL28374241 | 0.76 | KDM4E (0.45) | MEN1KMT2AMAPK1CYP19A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102146080-B | Beta-carboline alkali derivative compounds and application thereof | XINJIANG HUASHIDAN PHARMACEUTICAL CO LTD | 2013-01-30 | — | — | CN | disclosed |