Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27908719 | 0.93 | MEN1 (0.42) | KDM4EMEN1KMT2AATMMAPK1 | |
| SCHEMBL27908716 | 0.89 | ABCB1 (0.41) | KDM4EMEN1KMT2ARAD52APOBEC3G | |
| SCHEMBL27891731 | 0.82 | KDM4E (0.45) | KDM4EMEN1KMT2AATMMAPK1 | |
| SCHEMBL27891749 | 0.78 | KMT2A (0.42) | KDM4EMEN1KMT2AATMMAPK1 | |
| SCHEMBL27891759 | 0.78 | MCL1 (0.48) | KDM4EMEN1KMT2AATMCYP1A2 | |
| SCHEMBL27939722 | 0.77 | CYP19A1 (0.50) | KDM4EMEN1KMT2AMAPK1CYP1A2 | |
| SCHEMBL27891739 | 0.77 | ABCB1 (0.41) | KDM4EMEN1KMT2AATMMAPK1 | |
| SCHEMBL28375498 | 0.76 | KDM4E (0.46) | KDM4EMEN1KMT2AMAPK1CYP1A2 | |
| SCHEMBL27891748 | 0.75 | MEN1 (0.44) | KDM4EMEN1KMT2AATMCYP19A1 | |
| SCHEMBL28374241 | 0.75 | KDM4E (0.45) | KDM4EMEN1KMT2AMAPK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102146080-B | Beta-carboline alkali derivative compounds and application thereof | XINJIANG HUASHIDAN PHARMACEUTICAL CO LTD | 2013-01-30 | — | — | CN | claimed |