SCHEMBL27891740

SCHEMBL27891740

COc1cc2oc(-c3ccccc3)c(O)c(=O)c2c(O)c1OC

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MKNK2 Q9HBH9 1/20 0.74
ABCB1 P08183 5/20 0.70
ABCG2 Q9UNQ0 2/20 0.70
MAPT P10636 2/20 0.63
KDM4E B2RXH2 1/20 0.63
ALDH1A1 P00352 1/20 0.63
GAA P10253 1/20 0.63
ALOX5 P09917 2/20 0.61
TUBB4A P04350 4/20 0.57
TUBB P07437 4/20 0.57
TUBA3C P0DPH7 4/20 0.57
TUBA1B P68363 4/20 0.57
TUBA4A P68366 4/20 0.57
TUBB4B P68371 4/20 0.57
TUBB3 Q13509 4/20 0.57
TUBB2A Q13885 4/20 0.57
TUBB8 Q3ZCM7 4/20 0.57
TUBA3E Q6PEY2 4/20 0.57
TUBA1A Q71U36 4/20 0.57
TUBA1C Q9BQE3 4/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28647308 0.92 ABCB1 (0.81) MKNK2ABCB1ABCG2MAPTALOX5
SCHEMBL28066116 0.92 MKNK2 (0.63) MKNK2ABCB1ABCG2MAPTKDM4E
SCHEMBL28040768 0.90 MAPT (0.63) MKNK2ABCB1ABCG2MAPTKDM4E
SCHEMBL1144456 0.90 ABCB1 (0.86) MKNK2ABCB1ABCG2MAPTKDM4E
SCHEMBL21581945 0.90 ABCG2 (0.60) MKNK2ABCB1ABCG2MAPTKDM4E
Mikanin SCHEMBL26114621 0.89 MKNK2 (0.76) MKNK2ABCB1ABCG2MAPTKDM4E
Alnusin SCHEMBL2179417 0.88 TUBB4A (0.67) MKNK2ABCB1MAPTKDM4EALDH1A1
SCHEMBL28104130 0.87 ABCB1 (0.66) MKNK2ABCB1ABCG2MAPTKDM4E
SCHEMBL38660678 0.86 MKNK2 (0.84) MKNK2ABCB1ABCG2MAPTKDM4E
SCHEMBL29143220 0.85 MKNK2 (0.86) MKNK2ABCB1ABCG2ALOX5XDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109662984-B Application of laggera pterodonta and rosemary extract in medicine for resisting type II dengue virus 昆明医科大学 2022-07-26 CN claimed
CN-109662984-A The application of laggera pterodonta and Rosmarinus officinalis extract in anti-II type dengue virus drug 昆明医科大学 2019-04-23 CN claimed
CN-103735599-A Application of laggera pterodonta extract and composition in drug for resisting influenza A virus UNIV KUNMING MEDICAL 2014-04-23 CN claimed
CN-109662984-B Application of laggera pterodonta and rosemary extract in medicine for resisting type II dengue virus 昆明医科大学 2022-07-26 CN disclosed
CN-113164441-A Novel polymethoxyflavone compounds for skeletal muscle modulation, methods and uses thereof 雀巢产品有限公司 2021-07-23 CN disclosed
CN-109662984-A The application of laggera pterodonta and Rosmarinus officinalis extract in anti-II type dengue virus drug 昆明医科大学 2019-04-23 CN disclosed
CN-109239239-A Traditional Chinese medicine composition for clearing lung, eliminating phlegm, relieving cough and asthma and preparation method and application thereof 贵州优可安生物科技有限公司 2019-01-18 CN disclosed
CN-108186775-A A kind of mild Wound disinfectant and its preparation process 南通东康医疗科技有限公司 2018-06-22 CN disclosed
CN-103735599-B Herba laggera extract and application in anti-Alphavirus flu pharmaceutical for the composition 昆明医科大学 2016-10-05 CN disclosed
CN-102939997-B Extraction method and application of flavonoids compounds in camphor trees UNIV JINGGANGSHAN 2014-06-18 CN disclosed
CN-103735599-A Application of laggera pterodonta extract and composition in drug for resisting influenza A virus UNIV KUNMING MEDICAL 2014-04-23 CN disclosed
CN-102939997-A Extraction method and application of flavonoids compounds in camphor trees UNIV JINGGANGSHAN 2013-02-27 CN disclosed