Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA5 | O75582 | 11/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 6/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 6/20 | 0.35 |
| ▸ | RPS6KA4 | O75676 | 2/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29557414 | 0.75 | RPS6KA5 (0.41) | RPS6KA5KDM4EMAPTALDH1A1RPS6KA4 | |
| SCHEMBL30382329 | 0.75 | RPS6KA5 (0.41) | RPS6KA5KDM4EMAPTALDH1A1RPS6KA4 | |
| SCHEMBL256344 | 0.75 | RPS6KA5 (0.41) | RPS6KA5KDM4EMAPTALDH1A1RPS6KA4 | |
| SCHEMBL13296642 | 0.75 | RPS6KA5 (0.41) | RPS6KA5KDM4EMAPTALDH1A1RPS6KA4 | |
| SCHEMBL29603525 | 0.75 | RPS6KA5 (0.41) | RPS6KA5KDM4EMAPTALDH1A1RPS6KA4 | |
| SCHEMBL7844696 | 0.75 | RPS6KA5 (0.41) | RPS6KA5KDM4EMAPTALDH1A1RPS6KA4 | |
| SCHEMBL4659555 | 0.75 | RPS6KA5 (0.41) | RPS6KA5KDM4EMAPTALDH1A1RPS6KA4 | |
| SCHEMBL9633839 | 0.75 | RPS6KA5 (0.41) | RPS6KA5KDM4EMAPTALDH1A1RPS6KA4 | |
| SCHEMBL22771358 | 0.75 | RPS6KA5 (0.41) | RPS6KA5KDM4EMAPTALDH1A1RPS6KA4 | |
| SCHEMBL29626705 | 0.75 | GRIN1 (0.38) | RPS6KA5KDM4EMAPTALDH1A1GRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104159898-B | Process for preparing substituted 5-fluoro-1H-pyrazolopyridines | 阿德弗里奥药品有限责任公司 | 2017-01-18 | — | — | CN | disclosed |
| CN-104159898-B | Process for preparing substituted 5-fluoro-1H-pyrazolopyridines | 阿德弗里奥药品有限责任公司 | 2017-01-18 | — | — | CN | disclosed |
| CN-105503867-A | Method for producing substituted 5-fluoro-lH-pyrazolopyridines | ADVERIO PHARMA GMBH | 2016-04-20 | — | — | CN | disclosed |
| CN-102939289-B | Substituted 5-fluoro-1H-pyrazolopyridines and uses thereof | Bayer Pharma AG (DE) | 2016-01-20 | — | — | CN | disclosed |
| CN-102939289-B | Substituted 5-fluoro-1H-pyrazolopyridines and uses thereof | Bayer Pharma AG (DE) | 2016-01-20 | — | — | CN | disclosed |
| CN-104159898-A | Process for preparing substituted 5-fluoro-1H-pyrazolopyridines | Bayer Pharma AG | 2014-11-19 | — | — | CN | disclosed |
| CN-102939289-A | Substituted 5-fluoro-1H-pyrazolopyridines and uses thereof | Bayer Pharma AG | 2013-02-20 | — | — | CN | disclosed |