Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA5 | O75582 | 11/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | RPS6KA4 | O75676 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL7479800 | 0.98 | RPS6KA5 (0.40) | RPS6KA5POLBMAPK1ATMKDM4E | |
| SCHEMBL29603525 | 0.75 | RPS6KA5 (0.41) | RPS6KA5POLBKDM4EMAPTALDH1A1 | |
| SCHEMBL256344 | 0.75 | RPS6KA5 (0.41) | RPS6KA5KDM4EMAPTALDH1A1KMT2A | |
| SCHEMBL29557414 | 0.75 | RPS6KA5 (0.41) | RPS6KA5KDM4EMAPTALDH1A1KMT2A | |
| SCHEMBL9633839 | 0.75 | RPS6KA5 (0.41) | RPS6KA5ATMKDM4EMAPTALDH1A1 | |
| SCHEMBL4659555 | 0.75 | RPS6KA5 (0.41) | RPS6KA5KDM4EMAPTALDH1A1RPS6KA4 | |
| SCHEMBL13296642 | 0.75 | RPS6KA5 (0.41) | RPS6KA5POLBKDM4EMAPTALDH1A1 | |
| SCHEMBL30382329 | 0.75 | RPS6KA5 (0.41) | RPS6KA5ATMKDM4EMAPTALDH1A1 | |
| SCHEMBL22771358 | 0.75 | RPS6KA5 (0.41) | RPS6KA5POLBKDM4EMAPTALDH1A1 | |
| SCHEMBL27891755 | 0.75 | RPS6KA5 (0.41) | RPS6KA5KDM4EMAPTALDH1A1RPS6KA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0538297-B1 | ANTIVIRAL TETRAHYDROIMIDAZO 1,4]BENZODIAZEPIN-2-(THIO)ONES | JANSSEN PHARMACEUTICA NV (BE) | 2001-09-19 | — | — | EP | disclosed |