Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.45 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.45 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25764360 | 0.86 | MAPT (0.40) | MAPTMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL30310566 | 0.86 | MAPT (0.40) | MAPTMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL30310695 | 0.86 | CTSL (0.38) | MAPTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL24113246 | 0.86 | CTSL (0.38) | MAPTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL30009048 | 0.86 | MAPT (0.38) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL24113456 | 0.86 | MAPT (0.38) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL29443039 | 0.86 | CYP1A1 (0.41) | MAPTMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL19343270 | 0.86 | SCD (0.38) | MAPTMEN1KMT2AALDH1A1LY96 | |
| SCHEMBL22166661 | 0.86 | CYP1A1 (0.41) | MAPTMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL27891905 | 0.83 | POLB (0.45) | MAPTMEN1KMT2AALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102952062-B | Replace benzo-heterocycle compound and its preparation method and application | 中国医学科学院医药生物技术研究所 | 2016-06-08 | — | — | CN | disclosed |
| CN-102952062-A | Substituted benzoheterocyclic compounds and preparation method and application thereof | INST MEDICINAL BIOTECHNOLOGY | 2013-03-06 | — | — | CN | disclosed |