Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 6/20 | 0.32 |
| ▸ | CFD | P00746 | 2/20 | 0.32 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CCR3 | P51677 | 1/20 | 0.31 |
| ▸ | IL17A | Q16552 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2789221 | 1.00 | ALDH1A1 (0.33) | ALDH1A1TSHRKMT2ADPP4CFD | |
| SCHEMBL2788008 | 0.91 | DPP4 (0.33) | DPP4CFDPROKR1CYP2D6CCR3 | |
| SCHEMBL2788011 | 0.91 | DPP4 (0.33) | DPP4CFDPROKR1CYP2D6CCR3 | |
| SCHEMBL2819467 | 0.90 | PROKR1 (0.40) | ALDH1A1TSHRKMT2ADPP4PROKR1 | |
| SCHEMBL2789117 | 0.90 | DPP4 (0.32) | ALDH1A1TSHRKMT2ADPP4CFD | |
| SCHEMBL2789119 | 0.90 | DPP4 (0.32) | ALDH1A1TSHRKMT2ADPP4CFD | |
| SCHEMBL2792284 | 0.90 | DPP4 (0.32) | ALDH1A1TSHRKMT2ADPP4CFD | |
| SCHEMBL2790088 | 0.90 | DPP4 (0.32) | ALDH1A1TSHRKMT2ADPP4CFD | |
| SCHEMBL2791546 | 0.89 | ALDH1A1 (0.36) | ALDH1A1KMT2ADPP4CFDPROKR1 | |
| SCHEMBL2790241 | 0.89 | ALDH1A1 (0.36) | ALDH1A1KMT2ADPP4CFDPROKR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | claimed |
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |