Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 7/20 | 0.54 |
| ▸ | PORCN | Q9H237 | 10/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL246101 | 0.86 | WNT3A (0.65) | WNT3APORCN | |
| SCHEMBL248713 | 0.86 | WNT3A (0.52) | WNT3APORCN | |
| SCHEMBL27910498 | 0.86 | KCNH2 (0.50) | WNT3AKCNH2GRIN2BSMN1; SMN2 | |
| SCHEMBL248168 | 0.85 | WNT3A (0.55) | WNT3APORCN | |
| SCHEMBL27893431 | 0.84 | KCNH2 (0.53) | WNT3APORCNKCNH2GRIN2B | |
| SCHEMBL27893462 | 0.83 | KCNH2 (0.48) | WNT3APORCNKCNH2GRIN2B | |
| SCHEMBL27893473 | 0.83 | WNT3A (0.55) | WNT3APORCN | |
| Fumaric Acid SCHEMBL248599 | 0.82 | WNT3A (0.59) | WNT3APORCN | |
| Fumaric Acid SCHEMBL248600 | 0.82 | WNT3A (0.59) | WNT3APORCN | |
| SCHEMBL248408 | 0.80 | WNT3A (0.48) | WNT3APORCN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102958917-B | Compositions and methods for modulating the wnt signaling pathway | IRM LLC (BM) | 2014-10-08 | — | — | CN | disclosed |
| CN-102958917-A | Compositions and methods for modulating the wnt signaling pathway | IRM LLC | 2013-03-06 | — | — | CN | disclosed |