Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | RXRB | P28702 | 1/20 | 0.45 |
| ▸ | RXRG | P48443 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP26B1 | Q9NR63 | 3/20 | 0.44 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | RARA | P10276 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2790410 | 0.85 | NPC1 (0.58) | RXRARXRBRXRGMAPTCYP26B1 | |
| SCHEMBL32684923 | 0.81 | MEN1 (0.62) | KCNJ1KCNH2ATML3MBTL1MAPT | |
| SCHEMBL13411648 | 0.81 | CYP26A1 (0.55) | RXRARXRBRXRGMAPTALDH1A1 | |
| SCHEMBL13411688 | 0.80 | CYP26A1 (0.54) | RXRARXRBRXRGMAPTALDH1A1 | |
| SCHEMBL2789583 | 0.80 | CYP26A1 (0.49) | RXRARXRBRXRGALDH1A1MEN1 | |
| SCHEMBL13411654 | 0.79 | CYP26A1 (0.53) | RXRARXRBRXRGALDH1A1MEN1 | |
| SCHEMBL5083941 | 0.79 | RXRA (0.66) | RXRARXRBRXRGCYP26B1CYP26A1 | |
| SCHEMBL13411655 | 0.78 | CYP26A1 (0.52) | RXRARXRBRXRGALDH1A1MEN1 | |
| SCHEMBL13411672 | 0.78 | HPGD (0.50) | RXRARXRBRXRGALDH1A1MEN1 | |
| SCHEMBL13411657 | 0.78 | CYP26A1 (0.52) | RXRARXRBRXRGMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100056507-A1 | PHENYL DERIVATIVES AND THEIR USE AS A MEDICAMENT | IPSEN PHARMA S.A.S. (FR) | 2010-03-04 | — | — | US | claimed |
| US-20100056507-A1 | PHENYL DERIVATIVES AND THEIR USE AS A MEDICAMENT | IPSEN PHARMA S.A.S. (FR) | 2010-03-04 | — | — | US | disclosed |
| EP-2102162-A1 | PHENYLIC DERIVATIVES AND USE THEREOF AS DRUGS | IPSEN PHARMA S.A.S. (FR) | 2009-09-23 | — | — | EP | disclosed |
| WO-2008059128-A1 | PHENYLIC DERIVATIVES AND USE THEREOF AS DRUGS | IPSEN PHARMA S.A.S. (FR) | 2008-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056507-A1 | PHENYL DERIVATIVES AND THEIR USE AS A MEDICAMENT | CNR2, CNR1, TRPV1 | KCNJ1 2340/4885KCNH2 1913/4885ATM 4407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.