Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR8 | P51685 | 1/20 | 0.73 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.73 |
| ▸ | FAAH | O00519 | 19/20 | 0.68 |
| ▸ | MGLL | Q99685 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2791789 | 0.95 | CCR8 (0.69) | CCR8KCNH2FAAHMGLL | |
| SCHEMBL2790802 | 0.95 | CCR8 (0.71) | CCR8KCNH2FAAH | |
| SCHEMBL2791333 | 0.94 | FAAH (0.71) | CCR8KCNH2FAAHMGLL | |
| SCHEMBL2789561 | 0.94 | CCR8 (0.79) | CCR8KCNH2FAAHMGLL | |
| SCHEMBL2790090 | 0.91 | CCR8 (0.68) | CCR8KCNH2FAAHMGLL | |
| SCHEMBL5431975 | 0.86 | CCR8 (0.87) | CCR8KCNH2FAAH | |
| SCHEMBL3355088 | 0.86 | FAAH (0.74) | CCR8KCNH2FAAH | |
| SCHEMBL5197063 | 0.86 | CCR8 (0.74) | CCR8KCNH2FAAHMGLL | |
| SCHEMBL5399510 | 0.83 | CCR8 (0.67) | CCR8KCNH2FAAH | |
| SCHEMBL896968 | 0.82 | FAAH (0.63) | CCR8KCNH2FAAHMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010141817-A1 | HETEROARYL-SUBSTITUTED SPIROCYCLIC DIAMINE UREA MODULATORS OF FATTY ACID AMIDE HYDROLASE | JANSSEN PHARMACEUTICA NV (BE) | 2010-12-09 | — | — | WO | claimed |