Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.81 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene SCHEMBL27387362 | 0.90 | ACHE (0.87) | ACHENFE2L2TDP1SMN1; SMN2KMT2A | |
| SCHEMBL12689 | 0.90 | — | — | |
| SCHEMBL7025938 | 0.90 | — | — | |
| Iodide SCHEMBL27537208 | 0.87 | — | — | |
| Fluoride SCHEMBL28844251 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL27607289 | 0.87 | ACHE (0.93) | ACHENFE2L2TDP1SMN1; SMN2KMT2A | |
| Fluoride SCHEMBL27494802 | 0.87 | ACHE (0.93) | ACHENFE2L2TDP1SMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL29353267 | 0.87 | — | — | |
| Ammonia Solution, Strong SCHEMBL359474 | 0.87 | — | — | |
| SCHEMBL28221304 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110177786-A | Pyrazolo [1,5-A] pyridine compounds being substituted are as RET kinase inhibitor | 阿雷生物药品公司 | 2019-08-27 | — | — | CN | disclosed |
| CN-108883099-A | THIAZOLIDINONE COMPOUNDS AND USE THEREOF | 石全 | 2018-11-23 | — | — | CN | disclosed |
| CN-102603667-B | N-(2-chloro-6-methyl phenyl)-2-(phenyl acrylamide)thiazole-5-formamide derivative, and preparation method and use thereof | UNIV HEFEI TECHNOLOGY | 2014-04-30 | — | — | CN | disclosed |
| CN-103328449-A | Novel tetrahydroquinoline derivatives | HOFFMANN LA ROCHE | 2013-09-25 | — | — | CN | disclosed |
| CN-102958919-A | Novel tetrahydroquinoline derivatives | HOFFMANN LA ROCHE | 2013-03-06 | — | — | CN | disclosed |