Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 10/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16896765 | 0.77 | KAT2B (0.37) | KAT2BKDM4EALDH1A1MCL1 | |
| SCHEMBL13853065 | 0.74 | DRD4 (0.36) | KAT2B | |
| SCHEMBL13754457 | 0.74 | CYP2C19 (0.47) | KAT2BALDH1A1 | |
| SCHEMBL28312340 | 0.74 | KAT2B (0.47) | KAT2BKDM4EALDH1A1MCL1 | |
| SCHEMBL13656742 | 0.72 | KAT2B (0.40) | KAT2BKDM4EALDH1A1MCL1 | |
| SCHEMBL13762652 | 0.72 | KAT2B (0.40) | KAT2BKDM4EALDH1A1MCL1 | |
| SCHEMBL14047545 | 0.72 | DRD4 (0.52) | KDM4EALDH1A1MCL1 | |
| SCHEMBL14531021 | 0.71 | ALDH1A1 (0.47) | KAT2BKDM4EALDH1A1 | |
| SCHEMBL16305499 | 0.71 | KAT2B (0.39) | KAT2BKDM4EALDH1A1MCL1 | |
| SCHEMBL13456730 | 0.70 | KAT2B (0.35) | KAT2BKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103012375-B | Pyridyl triazole methyl substituted acridine derivative, preparation method and application thereof | UNIV GUIZHOU | 2014-04-09 | — | — | CN | claimed |
| CN-103012375-A | Pyridyl triazole methyl substituted acridine derivative, preparation method and application thereof | UNIV GUIZHOU | 2013-04-03 | — | — | CN | claimed |
| CN-103012375-B | Pyridyl triazole methyl substituted acridine derivative, preparation method and application thereof | UNIV GUIZHOU | 2014-04-09 | — | — | CN | disclosed |
| CN-103012375-A | Pyridyl triazole methyl substituted acridine derivative, preparation method and application thereof | UNIV GUIZHOU | 2013-04-03 | — | — | CN | disclosed |