Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 10/20 | 0.38 |
| ▸ | FAP | Q12884 | 7/20 | 0.38 |
| ▸ | PREP | P48147 | 5/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.37 |
| ▸ | ACE | P12821 | 4/20 | 0.36 |
| ▸ | REN | P00797 | 2/20 | 0.36 |
| ▸ | PITRM1 | Q5JRX3 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PEPD | P12955 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29091404 | 0.83 | DPP4 (0.33) | CYP3A4DPP4FAPPREPDPP7 | |
| SCHEMBL28054771 | 0.82 | ACE (0.45) | DPP4FAPDPP7DPP8DPP9 | |
| SCHEMBL20283280 | 0.81 | DPP4 (0.41) | CYP3A4DPP4FAPPREPDPP7 | |
| SCHEMBL27879636 | 0.81 | CHRM2 (0.37) | DPP4FAPPREPDPP8DPP9 | |
| SCHEMBL28797915 | 0.80 | DPP4 (0.56) | DPP4FAPPREPDPP7DPP8 | |
| SCHEMBL19104795 | 0.80 | SMN1; SMN2 (0.44) | CYP3A4DPP4FAPPREPDPP7 | |
| SCHEMBL17805810 | 0.78 | CYP3A4 (0.54) | CYP3A4DPP4FAPPREPDPP7 | |
| SCHEMBL28797927 | 0.78 | KMT2A (0.45) | CYP3A4DPP4FAPPREPDPP7 | |
| SCHEMBL7408815 | 0.77 | POLB (0.36) | CYP3A4DPP4 | |
| SCHEMBL28826381 | 0.77 | DPP4 (0.40) | DPP4FAPPREPDPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102791693-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2012-11-21 | — | — | CN | claimed |