Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | PREP | P48147 | 1/20 | 0.42 |
| ▸ | FAP | Q12884 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 6/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
| ▸ | MLX | Q9UH92 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27879621 | 0.85 | F2 (0.46) | CYP3A4PREPFAPDPP4CHRM3 | |
| SCHEMBL27879625 | 0.85 | F2 (0.46) | CYP3A4PREPFAPDPP4CHRM3 | |
| SCHEMBL27879610 | 0.83 | CYP3A4 (0.40) | KMT2AMEN1CYP3A4PREPFAP | |
| SCHEMBL28054669 | 0.83 | KDM4E (0.47) | KMT2AMEN1CYP3A4DPP4DPP8 | |
| SCHEMBL27896423 | 0.83 | CYP3A4 (0.40) | KMT2AMEN1CYP3A4PREPFAP | |
| SCHEMBL27828764 | 0.81 | TSHR (0.51) | KMT2AMEN1CYP3A4DPP4CHRM3 | |
| SCHEMBL27871773 | 0.79 | FKBP1A (0.42) | KMT2ACYP3A4DPP4DPP8 | |
| SCHEMBL15829016 | 0.79 | MEN1 (0.49) | KMT2AMEN1PREPFAPDPP4 | |
| SCHEMBL27896434 | 0.78 | CYP3A4 (0.39) | CYP3A4PREPFAPDPP4DPP8 | |
| SCHEMBL28797928 | 0.77 | ERAP2 (0.48) | KMT2AMEN1DPP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102459165-A | Anti-viral compounds | ABBOTT LAB | 2012-05-16 | — | — | CN | disclosed |