Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.68 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | MITF | O75030 | 1/20 | 0.56 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.56 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14859923 | 0.92 | ALDH1A1 (0.81) | ALDH1A1ALOX12KCNH2MAPTMEN1 | |
| SCHEMBL23068164 | 0.90 | ALDH1A1 (0.83) | ALDH1A1ALOX12KCNH2MAPTMEN1 | |
| SCHEMBL14860298 | 0.83 | ALDH1A1 (0.80) | ALDH1A1ALOX12MAPTMEN1KMT2A | |
| SCHEMBL15328268 | 0.83 | SMN1; SMN2 (0.77) | ALDH1A1ALOX12KCNH2MAPTMEN1 | |
| SCHEMBL15434970 | 0.82 | ALDH1A1 (1.00) | ALDH1A1ALOX12KCNH2MAPTMEN1 | |
| SCHEMBL14859851 | 0.82 | POLB (0.71) | ALDH1A1ALOX12MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL15328470 | 0.80 | ALDH1A1 (0.78) | ALDH1A1ALOX12KCNH2MAPTMEN1 | |
| SCHEMBL21357791 | 0.80 | ALDH1A1 (0.83) | ALDH1A1ALOX12KCNH2MAPTMEN1 | |
| SCHEMBL14865706 | 0.80 | ALDH1A1 (0.65) | ALDH1A1ALOX12MAPTMEN1KMT2A | |
| SCHEMBL15328351 | 0.79 | SMN1; SMN2 (0.71) | ALDH1A1ALOX12KCNH2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103003236-A | Novel thiourea or urea derivative, method for preparing the same and pharmaceutical composition for preventing or treating AIDS comprising the same as an active ingredient | AVIXGEN INC | 2013-03-27 | — | — | CN | claimed |
| CN-103003236-A | Novel thiourea or urea derivative, method for preparing the same and pharmaceutical composition for preventing or treating AIDS comprising the same as an active ingredient | AVIXGEN INC | 2013-03-27 | — | — | CN | disclosed |