Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.61 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.50 |
| ▸ | MMP1 | P03956 | 2/20 | 0.50 |
| ▸ | MMP2 | P08253 | 2/20 | 0.50 |
| ▸ | MMP9 | P14780 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | TNKS | O95271 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2225734 | 0.87 | PTGS1 (0.54) | PTGS2PTGS1ESR1TDP1NPC1 | |
| SCHEMBL8153855 | 0.87 | PTGS1 (0.54) | PTGS2PTGS1ESR1TDP1NPC1 | |
| Butane SCHEMBL20531195 | 0.87 | GLA (0.57) | PTGS2PTGS1ESR1TDP1GLA | |
| Alcohol SCHEMBL28968236 | 0.87 | GLA (0.57) | PTGS2PTGS1ESR1TDP1GLA | |
| Alcohol SCHEMBL29093584 | 0.87 | GLA (0.57) | PTGS2PTGS1ESR1TDP1GLA | |
| Alcohol SCHEMBL10389682 | 0.87 | GLA (0.57) | PTGS2PTGS1ESR1TDP1GLA | |
| SCHEMBL20303732 | 0.85 | MAPT (0.67) | ESR1TDP1GLANPC1LMNA | |
| SCHEMBL20303734 | 0.85 | MAPT (0.67) | ESR1TDP1GLANPC1LMNA | |
| SCHEMBL649508 | 0.85 | MAPT (0.67) | ESR1TDP1GLANPC1LMNA | |
| SCHEMBL3239009 | 0.85 | MAPT (0.67) | ESR1TDP1GLANPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103012181-B | Method for compounding caffeoyl dopamine | SUZHOU UUGENE BIOPHARMA CO LTD | 2014-06-04 | — | — | CN | disclosed |
| CN-103044279-A | Synthetic method of N-Coumaroyldopamine | SUZHOU UUGENE BIOPHARMA CO LTD | 2013-04-17 | — | — | CN | disclosed |
| CN-103012181-A | Method for compounding caffeoyl dopamine | SUZHOU UUGENE BIOPHARMA CO LTD | 2013-04-03 | — | — | CN | disclosed |