Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.41 |
| ▸ | LMNA | P02545 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27899074 | 0.90 | SLC1A5 (0.40) | SMN1; SMN2MAPTSLC1A5PTGER1PTGER4 | |
| SCHEMBL27899007 | 0.86 | HTT (0.40) | SMN1; SMN2LMNAMAPTPKMPTGER1 | |
| SCHEMBL27899276 | 0.84 | HTT (0.38) | SMN1; SMN2LMNAMAPTPTGER1PTGER4 | |
| SCHEMBL2253220 | 0.83 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNAMAPTPKMSLC1A5 | |
| SCHEMBL27899070 | 0.83 | CRBN (0.44) | SMN1; SMN2LMNAHTTMEN1KMT2A | |
| SCHEMBL27881791 | 0.82 | CRBN (0.51) | SMN1; SMN2LMNAHTTCRBNIKZF3 | |
| SCHEMBL28802083 | 0.81 | CRBN (0.53) | SMN1; SMN2LMNAHTTCRBNIKZF3 | |
| SCHEMBL27899016 | 0.81 | CRBN (0.48) | CRBNIKZF3 | |
| SCHEMBL27899082 | 0.81 | CRBN (0.48) | SMN1; SMN2LMNAHTTCRBNIKZF3 | |
| SCHEMBL27899081 | 0.81 | CRBN (0.44) | SMN1; SMN2LMNAHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102822165-A | Arylmethoxy isoindoline derivatives and compositions comprising and methods of using the same | CELGENE CORP | 2012-12-12 | — | — | CN | disclosed |