Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1273252 | 0.82 | ALDH1A1 (0.49) | LMNAALDH1A1HCAR2KMT2ATDP1 | |
| SCHEMBL4622404 | 0.81 | ALDH1A1 (0.51) | LMNAALDH1A1HCAR2KMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL10636148 | 0.80 | ALDH1A1 (0.50) | LMNAALDH1A1HCAR2KMT2ATDP1 | |
| SCHEMBL27963832 | 0.80 | ALDH1A1 (0.41) | LMNAALDH1A1HCAR2KMT2ATDP1 | |
| SCHEMBL28878826 | 0.79 | ALDH1A1 (0.43) | LMNAALDH1A1HCAR2KMT2ATDP1 | |
| SCHEMBL9298930 | 0.79 | ALDH1A1 (0.51) | LMNAALDH1A1KMT2ATDP1MAPK1 | |
| SCHEMBL7398999 | 0.78 | ALDH1A1 (0.50) | LMNAALDH1A1KMT2ATDP1MAPK1 | |
| SCHEMBL10789564 | 0.78 | ALDH1A1 (0.50) | LMNAALDH1A1HCAR2KMT2ATDP1 | |
| SCHEMBL4623371 | 0.78 | ALDH1A1 (0.55) | LMNAALDH1A1HCAR2KMT2ATDP1 | |
| SCHEMBL2387321 | 0.77 | ALDH1A1 (0.38) | LMNAALDH1A1HCAR2KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104693193-A | Arylmethoxy isoindoline derivatives and compositions comprising and methods of using the same | CELGENE CORP | 2015-06-10 | — | — | CN | disclosed |
| CN-102822165-B | Arylmethoxy isoindoline derivatives and compositions comprising and methods of using the same | CELGENE CORP | 2015-02-25 | — | — | CN | disclosed |
| CN-102822165-A | Arylmethoxy isoindoline derivatives and compositions comprising and methods of using the same | CELGENE CORP | 2012-12-12 | — | — | CN | disclosed |