Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 13/20 | 0.67 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL695697 | 0.99 | REN (0.66) | RENCYP3A4KCNH2 | |
| SCHEMBL2792552 | 0.95 | REN (0.63) | RENCYP3A4KCNH2 | |
| Hydrochloric Acid SCHEMBL695392 | 0.94 | REN (0.62) | RENCYP3A4KCNH2 | |
| Hydrochloric Acid SCHEMBL696345 | 0.94 | REN (0.62) | RENCYP3A4KCNH2 | |
| SCHEMBL2788513 | 0.93 | REN (0.77) | RENCYP3A4 | |
| SCHEMBL694821 | 0.93 | REN (0.77) | RENCYP3A4 | |
| Hydrochloric Acid SCHEMBL694530 | 0.92 | REN (0.76) | RENCYP3A4 | |
| Hydrochloric Acid SCHEMBL2691553 | 0.92 | REN (0.76) | RENCYP3A4 | |
| Hydrochloric Acid SCHEMBL695376 | 0.92 | REN (0.76) | RENCYP3A4 | |
| SCHEMBL695702 | 0.91 | REN (0.73) | RENCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010122580-A2 | NOVEL COMPOUNDS AS INHIBITORS OF RENIN | CADILA HEALTHCARE LIMITED (IN) | 2010-10-28 | — | — | WO | claimed |