Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.69 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.69 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | RAD52 | P43351 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GFER | P55789 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | SORD | Q00796 | 1/20 | 0.46 |
| ▸ | OGA | O60502 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13018736 | 0.81 | HRH3 (0.70) | HRH3HRH4SORDOGAROCK1 | |
| SCHEMBL2166051 | 0.81 | HRH4 (1.00) | HRH3HRH4 | |
| SCHEMBL20445925 | 0.81 | HRH3 (0.65) | HRH3HRH4SORDROCK1 | |
| SCHEMBL17626789 | 0.81 | HRH3 (0.65) | HRH3HRH4SORDOGAROCK1 | |
| SCHEMBL15260204 | 0.81 | HRH3 (0.51) | HRH3HRH4SORDOGA | |
| SCHEMBL26440599 | 0.80 | HRH3 (0.59) | HRH3HRH4KDM4ESORDOGA | |
| SCHEMBL14880196 | 0.79 | HRH3 (0.71) | HRH3HRH4SMN1; SMN2SORDOGA | |
| SCHEMBL17626748 | 0.79 | HRH3 (0.71) | HRH3HRH4SORDOGAROCK1 | |
| SCHEMBL23582282 | 0.79 | HRH3 (0.53) | HRH3HRH4KDM4ESORDOGA | |
| Bromide SCHEMBL20445910 | 0.78 | HRH3 (0.69) | HRH3HRH4SMN1; SMN2SORDOGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102775400-A | N-(4-(4-ethyl piperazine-1-yl)pyrimidine-2-yl)amide or pharmaceutically acceptable salt thereof, and preparation method and application thereof | ZHONGYU WANG | 2012-11-14 | — | — | CN | disclosed |
| CN-102775400-A | N-(4-(4-ethyl piperazine-1-yl)pyrimidine-2-yl)amide or pharmaceutically acceptable salt thereof, and preparation method and application thereof | ZHONGYU WANG | 2012-11-14 | — | — | CN | disclosed |