Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.59 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.59 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | SORD | Q00796 | 2/20 | 0.43 |
| ▸ | OGA | O60502 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.40 |
| ▸ | CDC7 | O00311 | 2/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17626789 | 0.81 | HRH3 (0.65) | HRH3HRH4SORDOGAROCK1 | |
| SCHEMBL27901036 | 0.80 | HRH3 (0.69) | HRH3HRH4SORDOGAROCK1 | |
| SCHEMBL24215682 | 0.79 | GRIN2D (0.46) | KDM4ECYP2D6 | |
| SCHEMBL30412512 | 0.79 | GRIN2D (0.46) | KDM4ECYP2D6 | |
| SCHEMBL17610057 | 0.78 | GRIN2D (0.46) | HRH3 | |
| SCHEMBL20445925 | 0.78 | HRH3 (0.65) | HRH3HRH4SORDROCK1CYP3A4 | |
| SCHEMBL17626748 | 0.76 | HRH3 (0.71) | HRH3HRH4SORDOGAROCK1 | |
| SCHEMBL14880196 | 0.76 | HRH3 (0.71) | HRH3HRH4SORDOGAROCK1 | |
| SCHEMBL31216500 | 0.75 | HPGDS (0.49) | OGAKDM4E | |
| SCHEMBL20124819 | 0.75 | HPGDS (0.49) | OGAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023066204-A1 | SIK INHIBITOR, COMPOSITION THEREOF, PREPARATION METHOD THEREFOR, AND USE THEREOF | 上海美悦生物科技发展有限公司 | 2023-04-27 | — | — | WO | disclosed |