Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 5/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7566657 | 0.79 | IDO1 (0.50) | IDO1KMT2AKDM4EAPPL3MBTL1 | |
| SCHEMBL21447792 | 0.77 | CYP3A4 (0.44) | KMT2AAPPRAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL27856388 | 0.77 | IDO1 (0.52) | IDO1KMT2AAPPNPC1RAB9A | |
| SCHEMBL28286129 | 0.77 | AGXT (0.52) | IDO1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28802270 | 0.77 | PTPRC (0.33) | — | |
| SCHEMBL1425850 | 0.76 | TSHR (0.52) | IDO1KMT2ANPC1LMNARAB9A | |
| SCHEMBL27916260 | 0.75 | IDO1 (0.58) | IDO1MAOBFFAR1FFAR4MAOA | |
| Ammonia Solution, Strong SCHEMBL5804107 | 0.74 | TSHR (0.50) | IDO1KMT2ANPC1LMNARAB9A | |
| Hydrochloric Acid SCHEMBL7794099 | 0.74 | TSHR (0.50) | IDO1KMT2ANPC1LMNARAB9A | |
| SCHEMBL24133222 | 0.74 | IDO1 (0.55) | IDO1KMT2ANPC1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108997233-A | A kind of synthetic method of (Z)-configuration enester triazole compounds | 陕西师范大学 | 2018-12-14 | — | — | CN | disclosed |
| CN-108997231-A | (E)-configuration enester triazole compounds synthetic method | 陕西师范大学 | 2018-12-14 | — | — | CN | disclosed |
| CN-106632103-B | A kind of synthetic method of the triazole of the structure containing sulphoxide imine | 华侨大学 | 2018-11-27 | — | — | CN | disclosed |
| CN-103012379-B | Phenylalanine derivatives, preparation method and application thereof | UNIV ZHEJIANG | 2014-12-24 | — | — | CN | disclosed |
| CN-102850283-B | Triazolyl-containing amino-dithio formic ether compound as well as preparation method and application of compound | ZHENGZHOU UNIVERSITY (CN) | 2014-10-22 | — | — | CN | disclosed |
| CN-103012379-A | Phenylalanine derivatives, preparation method and application thereof | UNIV ZHEJIANG | 2013-04-03 | — | — | CN | disclosed |
| CN-102850283-A | Triazolyl-containing amino-dithio formic ether compound as well as preparation method and application of compound | UNIV ZHENGZHOU | 2013-01-02 | — | — | CN | disclosed |