Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGXT | P21549 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5229035 | 0.79 | AGXT (0.54) | AGXTCA1CA2CA9NPC1 | |
| SCHEMBL7566657 | 0.79 | IDO1 (0.50) | CA2IDO1KMT2ACYP2C19L3MBTL1 | |
| SCHEMBL27646961 | 0.78 | IDO1 (0.55) | AGXTCA1CA2CA9NPC1 | |
| SCHEMBL27856388 | 0.77 | IDO1 (0.52) | AGXTCA1CA2CA9NPC1 | |
| SCHEMBL21447792 | 0.77 | CYP3A4 (0.44) | CA2CA9RAB9AMAOBKMT2A | |
| SCHEMBL27901547 | 0.77 | IDO1 (0.52) | CA1CA2CA9NPC1RAB9A | |
| SCHEMBL5229041 | 0.77 | AGXT (0.52) | AGXTCA1CA2CA9NPC1 | |
| SCHEMBL3794389 | 0.77 | PIR (0.50) | CA1CA2CA9KMT2ASMN1; SMN2 | |
| SCHEMBL1014576 | 0.77 | IDO1 (0.57) | NPC1RAB9AMAOBIDO1KMT2A | |
| SCHEMBL1425850 | 0.76 | TSHR (0.52) | AGXTCA1CA2CA9NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105418609-A | 4-(1,2,3-triazole substituted anilino)-pyridinopyrimidinones derivative and preparation method and application thereof | UNIV SHANDONG | 2016-03-23 | — | — | CN | claimed |
| US-20250109095-A1 | METHOD FOR PREPARING OXIME DERIVATIVE | SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) | 2025-04-03 | — | — | US | disclosed |
| WO-2023101319-A1 | METHOD FOR PREPARING OXIME DERIVATIVE | 서울대학교산학협력단 | 2023-06-08 | — | — | WO | disclosed |
| CN-107118168-B | A kind of copper catalyzes and synthesizes Trifluoromethyl-1, the method for 2,4- triazineon compounds | 福州大学 | 2019-10-15 | — | — | CN | disclosed |
| CN-106380465-B | 2,4- disubstituted quinazoline compounds and its preparation method and application containing 1,2,3- triazole structure unit | 郑州大学 | 2019-03-12 | — | — | CN | disclosed |
| CN-107118168-A | A kind of method that copper catalysis synthesizes the triazineon compounds of trifluoromethyl 1,2,4 | 福州大学 | 2017-09-01 | — | — | CN | disclosed |
| CN-105418609-B | 4 (1,2,3 triazole substituted anilinic) pyridines a pair of horses going side by side pyrimidone derivatives and preparation method and application | 山东大学 | 2017-06-23 | — | — | CN | disclosed |
| CN-106380465-A | 1,2,3-Triazole structure unit-containing 2,4-disubstituted quinazoline compounds, and preparation method and use thereof | 郑州大学 | 2017-02-08 | — | — | CN | disclosed |
| CN-105418609-A | 4-(1,2,3-triazole substituted anilino)-pyridinopyrimidinones derivative and preparation method and application thereof | UNIV SHANDONG | 2016-03-23 | — | — | CN | disclosed |
| CN-103044341-B | 1, 2, 3-triazole-dithiocarbamate-urea complex, as well as preparation method and application thereof | UNIV ZHENGZHOU | 2015-07-01 | — | — | CN | disclosed |
| CN-103910644-B | Beta-enaminone ester compounds, and synthesis method and application of beta-enaminone ester compounds | UNIV GUANGXI NORMAL | 2015-06-24 | — | — | CN | disclosed |
| CN-102850283-B | Triazolyl-containing amino-dithio formic ether compound as well as preparation method and application of compound | ZHENGZHOU UNIVERSITY (CN) | 2014-10-22 | — | — | CN | disclosed |
| CN-103910644-A | Beta-enaminone ester compounds, and synthesis method and application of beta-enaminone ester compounds | UNIV GUANGXI NORMAL | 2014-07-09 | — | — | CN | disclosed |
| CN-103113314-A | Method for synthesizing aliphatic 1-substitution-1,2,3-triazole through aliphatic azide | UNIV TONGJI | 2013-05-22 | — | — | CN | disclosed |
| CN-103054869-A | Application of amino dithio formic ester compound with triazolyl in preparing medicine taking LSD1 (Lysine Specificity Demethylase 1) as target | UNIV ZHENGZHOU | 2013-04-24 | — | — | CN | disclosed |
| CN-103044341-A | 1, 2, 3-triazole-dithiocarbamate-urea complex, as well as preparation method and application thereof | UNIV ZHENGZHOU | 2013-04-17 | — | — | CN | disclosed |
| CN-102850283-A | Triazolyl-containing amino-dithio formic ether compound as well as preparation method and application of compound | UNIV ZHENGZHOU | 2013-01-02 | — | — | CN | disclosed |
| CN-102336718-A | Fluorine-containing triazole derivatives and preparation method thereof | UNIV SHANGHAI | 2012-02-01 | — | — | CN | disclosed |
| CN-102153580-A | Benzotriazole or naphthotriazole derivative and synthesis method thereof | UNIV SHANGHAI | 2011-08-17 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250109095-A1 | METHOD FOR PREPARING OXIME DERIVATIVE | NOS2, NOS1, NOS3 | AGXT 2976/4885CA1 1522/4885CA2 962/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.