Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 4/20 | 0.73 |
| ▸ | IL1RN | P18510 | 2/20 | 0.63 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.63 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.63 |
| ▸ | CTSL | P07711 | 2/20 | 0.63 |
| ▸ | CTSS | P25774 | 1/20 | 0.63 |
| ▸ | CTSK | P43235 | 1/20 | 0.63 |
| ▸ | KLK7 | P49862 | 1/20 | 0.62 |
| ▸ | ACE | P12821 | 1/20 | 0.60 |
| ▸ | CCKBR | P32239 | 4/20 | 0.58 |
| ▸ | NMBR | P28336 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27902193 | 1.00 | TACR1 (0.73) | TACR1IL1RNERAP2ERAP1CTSL | |
| SCHEMBL27885257 | 0.95 | TACR1 (0.77) | TACR1IL1RNERAP2ERAP1CTSL | |
| SCHEMBL27885259 | 0.95 | TACR1 (0.77) | TACR1IL1RNERAP2ERAP1CTSL | |
| SCHEMBL27951091 | 0.94 | TACR1 (0.74) | TACR1IL1RNERAP2ERAP1CTSL | |
| SCHEMBL27951092 | 0.94 | TACR1 (0.74) | TACR1IL1RNERAP2ERAP1CTSL | |
| SCHEMBL29397912 | 0.94 | TACR1 (0.82) | TACR1CTSLCTSSCTSKKLK7 | |
| SCHEMBL8697113 | 0.94 | TACR1 (0.82) | TACR1CTSLCTSSCTSKKLK7 | |
| SCHEMBL16464197 | 0.94 | TACR1 (0.82) | TACR1CTSLCTSSCTSKKLK7 | |
| SCHEMBL5355362 | 0.94 | TACR1 (0.82) | TACR1CTSLCTSSCTSKKLK7 | |
| SCHEMBL4840264 | 0.91 | TACR1 (0.71) | TACR1IL1RNERAP2ERAP1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102807601-B | Aminoacyl-tryptophanyl-5-methoxytryptamine and preparation method and application thereof | UNIV CAPITAL MEDICAL SCIENCES | 2014-02-26 | — | — | CN | disclosed |
| CN-102807601-A | Aminoacyl-tryptophanyl-5-methoxytryptamine and preparation method and application thereof | UNIV CAPITAL MEDICAL | 2012-12-05 | — | — | CN | disclosed |