Benzene

Benzene

SCHEMBL27902258

Cc1ccc(S)c(S)c1.c1ccccc1

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 5/20 0.43
CYP2A6 P11509 4/20 0.41
CYP1A2 P05177 4/20 0.41
TDP1 Q9NUW8 5/20 0.40
LMNA P02545 1/20 0.38
TSHR P16473 1/20 0.38
ALOX12 P18054 1/20 0.38
PSMD14 O00487 1/20 0.38
COPS5 Q92905 1/20 0.38
TP53 P04637 2/20 0.36
CYP3A4 P08684 1/20 0.36
THRB P10828 1/20 0.36
ALOX15 P16050 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TRPA1 O75762 1/20 0.36
NQO2 P16083 1/20 0.36
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29373274 0.94
SCHEMBL331198 0.94
SCHEMBL11330698 0.92 TDP1 (0.44) ACHECYP2A6CYP1A2TDP1LMNA
Arsenic SCHEMBL27863102 0.92 CYP2A6 (0.43) ACHECYP2A6CYP1A2TDP1LMNA
SCHEMBL28693453 0.92 CYP2A6 (0.43) ACHECYP2A6CYP1A2TDP1LMNA
SCHEMBL30929155 0.92 CYP2A6 (0.43) ACHECYP2A6CYP1A2TDP1LMNA
Hydrochloric Acid SCHEMBL31606798 0.92 CYP2A6 (0.43) ACHECYP2A6CYP1A2TDP1LMNA
SCHEMBL1157705 0.92 CYP2A6 (0.43) ACHECYP2A6CYP1A2TDP1LMNA
SCHEMBL548060 0.92 CYP2A6 (0.43) ACHECYP2A6CYP1A2TDP1LMNA
Bromide SCHEMBL27589361 0.89 CYP2A6 (0.41) ACHECYP2A6CYP1A2TDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101117445-B Optical absorption pigment and optical absorption material SUMITOMO SEIKA CHEMICALS 2012-11-28 CN claimed
CN-101117445-B Optical absorption pigment and optical absorption material SUMITOMO SEIKA CHEMICALS 2012-11-28 CN disclosed