Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.39 |
| ▸ | ACHE | P22303 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.34 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL331198 | 0.97 | — | — | |
| SCHEMBL29373274 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL31606798 | 0.94 | CYP2A6 (0.43) | CYP2A6CYP1A2TDP1ACHETP53 | |
| SCHEMBL28693453 | 0.94 | CYP2A6 (0.43) | CYP2A6CYP1A2TDP1ACHETP53 | |
| SCHEMBL1157705 | 0.94 | CYP2A6 (0.43) | CYP2A6CYP1A2TDP1ACHETP53 | |
| SCHEMBL30929155 | 0.94 | CYP2A6 (0.43) | CYP2A6CYP1A2TDP1ACHETP53 | |
| Arsenic SCHEMBL27863102 | 0.94 | CYP2A6 (0.43) | CYP2A6CYP1A2TDP1ACHETP53 | |
| Benzene SCHEMBL27902258 | 0.92 | ACHE (0.43) | CYP2A6CYP1A2TDP1ACHETP53 | |
| Bromide SCHEMBL27589361 | 0.92 | CYP2A6 (0.41) | CYP2A6CYP1A2TDP1ACHETP53 | |
| SCHEMBL11330698 | 0.89 | TDP1 (0.44) | CYP2A6CYP1A2TDP1ACHETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2117611-B1 | BIOFILM-INHIBITING MEDICAL PRODUCTS | COOK MEDICAL TECHNOLOGIES LLC (US) | 2014-07-30 | — | — | EP | claimed |
| US-8343536-B2 | Biofilm-inhibiting medical products | COOK BIOTECH INCORPORATED (US) | 2013-01-01 | — | — | US | claimed |
| EP-2117611-A2 | BIOFILM-INHIBITING MEDICAL PRODUCTS | Cook Incorporated (US) | 2009-11-18 | — | — | EP | claimed |
| US-20080181950-A1 | BIOFILM-INHIBITING MEDICAL PRODUCTS | COOK INCORPORATED (US) | 2008-07-31 | — | — | US | claimed |
| WO-2008092011-A2 | BIOFILM-INHIBITING MEDICAL PRODUCTS | COOK INCORPORATED (US) | 2008-07-31 | — | — | WO | claimed |
| US-12036200-B2 | Bismuth-thiol compositions and methods for treating wounds | MICROBION CORPORATION (US) | 2024-07-16 | — | — | US | disclosed |
| US-11974978-B2 | Bismuth-thiol compositions and methods for treating wounds | MICROBION CORPORATION (US) | 2024-05-07 | — | — | US | disclosed |
| US-20230255925-A1 | BISMUTH-THIOL COMPOSITIONS AND METHODS FOR TREATING WOUNDS | MICROBION CORPORATION | 2023-08-17 | — | — | US | disclosed |
| US-20230165808-A1 | BISMUTH-THIOL COMPOSITIONS AND METHODS OF USE | MICROBION CORPORATION | 2023-06-01 | — | — | US | disclosed |
| US-20230149340-A1 | BISMUTH-THIOLS AS ANTISEPTICS FOR EPITHELIAL TISSUES, ACUTE AND CHRONIC WOUNDS, BACTERIAL BIOFILMS AND OTHER INDICATIONS | MICROBION CORPORATION | 2023-05-18 | — | — | US | disclosed |
| US-20230124862-A1 | BISMUTH THIOL COMPOUNDS AND COMPOSITIONS AND METHODS OF TREATING MICROBIAL CO-INFECTIONS | MICROBION CORPORATION | 2023-04-20 | — | — | US | disclosed |
| US-11564903-B2 | Bismuth-thiols as antiseptics for epithelial tissues, acute and chronic wounds, bacterial biofilms and other indications | MICROBION CORPORATION (US) | 2023-01-31 | — | — | US | disclosed |
| EP-1702621-A2 | Metal/Thiol biocides | Winthrop-University Hospital (US) | 2006-09-20 | — | — | EP | disclosed |
| US-20060147496-A1 | Diagnosis of irritable bowel disorders; fibromyalgia; chronic fatique syndrome; antidepressants; tinnitus; autism; autoimmune disease; Crohn's disease; quantitative analysis of serotonine, bile acid in sample | CEDARS-SINAI MEDICAL CENTER (US) | 2006-07-06 | — | — | US | disclosed |
| EP-1385476-A4 | METHODS OF DIAGNOSING AND TREATING SMALL INTESTINAL BACTERIAL OVERGROWTH (SIBO) AND SIBO-RELATED CONDITIONS | CEDARS SINAI MEDICAL CENTER (US) | 2006-06-14 | — | — | EP | disclosed |
| US-7048906-B2 | Calibration; administering antiseptic compound | CEDARS-SINAI MEDICAL CENTER (US) | 2006-05-23 | — | — | US | disclosed |
| EP-1064004-B1 | METAL/THIOL BIOCIDES | UNIV WINTHROP HOSPITAL (US) | 2006-01-04 | — | — | EP | disclosed |
| EP-1385476-A2 | METHODS OF DIAGNOSING AND TREATING SMALL INTESTINAL BACTERIAL OVERGROWTH (SIBO) AND SIBO-RELATED CONDITIONS | CEDARS-SINAI MEDICAL CENTER (US) | 2004-02-04 | — | — | EP | disclosed |
| WO-2002083926-A2 | METHODS OF DIAGNOSING AND TREATING SMALL INTESTINAL BACTERIAL OVERGROWTH (SIBO) AND SIBO-RELATED CONDITIONS | CEDARS-SINAI MEDICAL CENTER (US) | 2002-10-24 | — | — | WO | disclosed |
| US-20020039599-A1 | Calibration; administering antiseptic compound | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-04-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230255925-A1 | BISMUTH-THIOL COMPOSITIONS AND METHODS FOR TREATING WOUNDS | TST, CBS, CTH | CYP2A6 1929/4885CYP1A2 2366/4885TDP1 2442/4885 |
| US-20230165808-A1 | BISMUTH-THIOL COMPOSITIONS AND METHODS OF USE | TST, CTH, CBS | CYP2A6 1155/4885CYP1A2 1383/4885TDP1 2274/4885 |
| US-20230149340-A1 | BISMUTH-THIOLS AS ANTISEPTICS FOR EPITHELIAL TISSUES, ACUTE AND CHRONIC WOUNDS, BACTERIAL BIOFILMS AND OTHER INDICATIONS | TST, BTD, BTF3 | CYP2A6 3305/4885CYP1A2 4369/4885TDP1 3685/4885 |
| US-11974978-B2 | Bismuth-thiol compositions and methods for treating wounds | TST, CBS, CTH | CYP2A6 1929/4885CYP1A2 2366/4885TDP1 2442/4885 |
| US-20230124862-A1 | BISMUTH THIOL COMPOUNDS AND COMPOSITIONS AND METHODS OF TREATING MICROBIAL CO-INFECTIONS | MPST, TST, TPMT | CYP2A6 534/4885CYP1A2 976/4885TDP1 3517/4885 |
| US-11564903-B2 | Bismuth-thiols as antiseptics for epithelial tissues, acute and chronic wounds, bacterial biofilms and other indications | TST, BTD, BTF3 | CYP2A6 3305/4885CYP1A2 4369/4885TDP1 3685/4885 |
| US-12036200-B2 | Bismuth-thiol compositions and methods for treating wounds | TST, CBS, CTH | CYP2A6 1929/4885CYP1A2 2366/4885TDP1 2442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.