Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.60 |
| ▸ | PRKCA | P17252 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11005205 | 0.93 | NAAA (0.71) | NAAAPRKCA | |
| SCHEMBL8690279 | 0.85 | NAAA (0.72) | NAAAPRKCASMN1; SMN2 | |
| SCHEMBL5463377 | 0.82 | NAAA (0.41) | NAAA | |
| SCHEMBL4978860 | 0.82 | NAAA (0.86) | NAAAPRKCASMN1; SMN2 | |
| SCHEMBL8691439 | 0.82 | NAAA (0.79) | NAAAPRKCASMN1; SMN2 | |
| SCHEMBL8690525 | 0.80 | NAAA (0.86) | NAAAKDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL32662564 | 0.80 | NAAA (0.83) | NAAAPRKCASMN1; SMN2 | |
| SCHEMBL1177076 | 0.80 | NAAA (0.86) | NAAAKDM4ESMN1; SMN2 | |
| SCHEMBL4978268 | 0.80 | NAAA (0.82) | NAAAPRKCASMN1; SMN2 | |
| SCHEMBL28906804 | 0.79 | NAAA (0.64) | NAAAPRKCASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103097375-B | Cyclohexyl-azetidine the antagonist of CCR2 | JANSSEN PHARMACEUTICA N.V. (BE) | 2015-08-12 | — | — | CN | disclosed |
| CN-103097375-A | Cyclohexyl-azetidinyl antagonists of CCR2 | JANSSEN PHARMACEUTICA NV | 2013-05-08 | — | — | CN | disclosed |