Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.32 |
| ▸ | AKT1 | P31749 | 2/20 | 0.32 |
| ▸ | AKT2 | P31751 | 2/20 | 0.32 |
| ▸ | AKT3 | Q9Y243 | 2/20 | 0.32 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3719199 | 0.87 | AKT1 (0.44) | SLC6A2SLC6A4SLC6A3AKT1AKT2 | |
| SCHEMBL3719200 | 0.87 | AKT1 (0.44) | SLC6A2SLC6A4SLC6A3AKT1AKT2 | |
| SCHEMBL3719193 | 0.87 | AKT1 (0.44) | SLC6A2SLC6A4SLC6A3AKT1AKT2 | |
| SCHEMBL11961245 | 0.87 | AKT1 (0.44) | SLC6A2SLC6A4SLC6A3AKT1AKT2 | |
| SCHEMBL27902774 | 0.81 | MAPK1 (0.35) | MAPK1 | |
| SCHEMBL11961825 | 0.81 | AKT1 (0.37) | MAPK1SLC6A2SLC6A4SLC6A3AKT1 | |
| SCHEMBL27807351 | 0.81 | MAPK1 (0.35) | MAPK1LMNAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL27807423 | 0.81 | MAPK1 (0.35) | MAPK1LMNAMAPTSMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL28802497 | 0.81 | MAPK1 (0.35) | MAPK1 | |
| SCHEMBL3739679 | 0.78 | PIK3CD (0.39) | MAPK1LMNASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101965347-B | Pyrazolopyridines as kinase inhibitors | ARRAY BIOPHARMA INC | 2013-01-02 | — | — | CN | disclosed |