Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.39 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5463120 | 0.83 | GSK3B (0.48) | DAOGAAPKMALOX15HSD17B10 | |
| SCHEMBL4954917 | 0.80 | DAO (0.48) | DAOGAAPKMALOX15HSD17B10 | |
| SCHEMBL14496948 | 0.77 | GPR35 (0.46) | DAOGAAPKMALOX15HSD17B10 | |
| SCHEMBL27973248 | 0.76 | GAA (0.45) | DAOGAAPKMALOX15HSD17B10 | |
| SCHEMBL210529 | 0.76 | GPR35 (0.44) | DAOGAAPKMALOX15HSD17B10 | |
| SCHEMBL248655 | 0.75 | HSD17B10 (0.72) | DAOGAAPKMALOX15HSD17B10 | |
| SCHEMBL15893702 | 0.72 | GAA (0.41) | DAOGAAPKMALOX15HSD17B10 | |
| SCHEMBL21765884 | 0.70 | GAA (0.58) | POLBGAAPKMALOX15HSD17B10 | |
| SCHEMBL27579199 | 0.69 | GSK3B (0.66) | POLBDAOGAAHSD17B10GSK3B | |
| SCHEMBL208453 | 0.69 | GPR35 (0.44) | POLBDAOGAAPKMALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1826333-B | Diamine derivatives | DAIICHI SANKYO CO LTD | 2012-12-26 | — | — | CN | disclosed |