Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.68 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.56 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | KRAS | P01116 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.51 |
| ▸ | CFB | P00751 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29822827 | 0.85 | GAA (0.75) | GAAGRIN1GRIN2BPOLBDDAH1 | |
| SCHEMBL483337 | 0.85 | GAA (0.75) | GAAGRIN1GRIN2BPOLBDDAH1 | |
| SCHEMBL27902886 | 0.84 | GAA (0.68) | GAAGRIN1GRIN2BPOLBDDAH1 | |
| Bendazol SCHEMBL29539948 | 0.81 | GAA (1.00) | GAAGRIN1GRIN2BPOLBDDAH1 | |
| Bendazol SCHEMBL309393 | 0.81 | GAA (1.00) | GAAGRIN1GRIN2BPOLBDDAH1 | |
| SCHEMBL27902884 | 0.81 | GAA (0.68) | GAAGRIN1GRIN2BPOLBDDAH1 | |
| SCHEMBL230024 | 0.80 | GAA (0.78) | GAAGRIN1GRIN2BPOLBDDAH1 | |
| Bendazol SCHEMBL27823120 | 0.80 | GAA (0.96) | GAAGRIN1GRIN2BPOLBDDAH1 | |
| Bendazol SCHEMBL15015931 | 0.80 | GAA (0.96) | GAAGRIN1GRIN2BPOLBDDAH1 | |
| SCHEMBL2678741 | 0.77 | SMN1; SMN2 (0.69) | GAAGRIN1GRIN2BPOLBDDAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103058931-B | Four 2-(3', 5'-dihalo-benzyl) benzimidazole type novel compounds and preparation method thereof | GUANGDONG TONESET SCIENCE & TECHNOLOGY CO LTD | 2015-07-01 | — | — | CN | disclosed |
| CN-103058931-A | Four 2-(3', 5'-dihalo-benzyl) benzimidazole type novel compounds and preparation method thereof | GUANGDONG TONESET SCIENCE & TECHNOLOGY CO LTD | 2013-04-24 | — | — | CN | disclosed |