SCHEMBL2790458

SCHEMBL2790458

O=C1CCCN1CCOCCO

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.46
KMT2A Q03164 4/20 0.46
MEN1 O00255 2/20 0.46
TSHR P16473 3/20 0.44
PIK3CD O00329 1/20 0.42
PKM P14618 1/20 0.41
ADRA1B P35368 2/20 0.39
CYP1A2 P05177 1/20 0.39
CHRM2 P08172 1/20 0.39
CHRM4 P08173 1/20 0.39
CHRM5 P08912 1/20 0.39
CYP2D6 P10635 1/20 0.39
CHRM1 P11229 1/20 0.39
CYP2C9 P11712 1/20 0.39
CHRM3 P20309 1/20 0.39
CYP2C19 P33261 1/20 0.39
PDK2 Q15119 1/20 0.38
ADRA1A P35348 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2490366 0.98 POLB (0.45) POLBKMT2AMEN1TSHRPIK3CD
SCHEMBL2794567 0.93 KMT2A (0.41) POLBKMT2AMEN1TSHRPIK3CD
SCHEMBL7937319 0.91 KMT2A (0.51) POLBKMT2AMEN1TSHRPIK3CD
SCHEMBL19514128 0.89 KMT2A (0.50) POLBKMT2AMEN1TSHRPIK3CD
SCHEMBL9011466 0.87 PIK3CD (0.50) POLBKMT2AMEN1TSHRPIK3CD
SCHEMBL8560901 0.87 KMT2A (0.49) POLBKMT2AMEN1TSHRPIK3CD
SCHEMBL8558755 0.85 KMT2A (0.48) POLBKMT2AMEN1TSHRPIK3CD
SCHEMBL20687601 0.85 KMT2A (0.48) POLBKMT2AMEN1TSHRPIK3CD
SCHEMBL8559626 0.85 KMT2A (0.46) POLBKMT2AMEN1TSHRPIK3CD
SCHEMBL8561376 0.84 KMT2A (0.47) POLBKMT2AMEN1TSHRPIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2121559-B1 CATALYTIC METHOD FOR PRODUCING (METH)ACRYLIC ACID ESTERS OF N-HYDROXYALKYLATED LACTAMS BASF SE (DE) 2015-08-26 EP claimed
US-8476387-B2 Catalytic process for preparing (meth)acrylic esters of N-hydroxyalkylated lactams BASF SE (DE) 2013-07-02 US claimed
CN-101300220-B Catalytic process for preparing (meth) acrylic esters from N-hydroxyalkylated lactams BASF AG 2013-02-20 CN claimed
US-8367788-B2 Catalytic process for preparing (meth)acrylic esters of N-hydroxyalkylated lactams BASF SE (DE) 2013-02-05 US claimed
EP-1945602-B1 HYDROGEN-CATALYSED PROCESS FOR PREPARING (METH)ACRYLATES OF N-HYDROXY­ALKYLATED LACTAMS BASF SE (DE) 2012-08-01 EP claimed
US-7750100-B2 Catalytic process for preparing (meth)acrylates from N-hydroxyalkylated lactams BASF AKTIENGESELLSCHAFT (DE) 2010-07-06 US claimed
US-20100113725-A1 CATALYTIC PROCESS FOR PREPARING (METH)ACRYLIC ESTERS OF N-HYDROXYALKYLATED LACTAMS BASF SE (DE) 2010-05-06 US claimed
US-20100010236-A1 CATALYTIC PROCESS FOR PREPARING (METH)ACRYLIC ESTERS OF N-HYDROXYALKYLATED LACTAMS BASF SE (DE) 2010-01-14 US claimed
CN-101622228-A Catalytic process for preparing (meth) acrylic esters of N-hydroxyalkylated lactams BASF SE 2010-01-06 CN claimed
EP-2121595-A1 METHOD FOR PRODUCING (METH)ACRYLIC ESTERS OF N-HYDROXYALKYLATED LACTAMS BASF SE (DE) 2009-11-25 EP claimed
EP-2121559-A1 CATALYTIC METHOD FOR PRODUCING (METH)ACRYLIC ACID ESTERS OF N-HYDROXYALKYLATED LACTAMS BASF SE (DE) 2009-11-25 EP claimed
CN-101300220-A Catalytic process for preparing (meth) acrylic esters from N-hydroxyalkylated lactams BASF AG (DE) 2008-11-05 CN claimed
WO-2008098885-A1 METHOD FOR PRODUCING (METH)ACRYLIC ESTERS OF N-HYDROXYALKYLATED LACTAMS BASF SE (DE) 2008-08-21 WO claimed
WO-2008098887-A1 CATALYTIC METHOD FOR PRODUCING (METH)ACRYLIC ACID ESTERS OF N-HYDROXYALKYLATED LACTAMS BASF SE (DE) 2008-08-21 WO claimed
EP-1945602-A1 HYDROGEN-CATALYSED PROCESS FOR PREPARING (METH)ACRYLATES OF N-HYDROXY­ALKYLATED LACTAMS BASF SE (DE) 2008-07-23 EP claimed
US-20070123673-A1 CATALYTIC PROCESS FOR PREPARING (METH)ACRYLATES FROM N-HYDROXYALKYLATED LACTAMS BASF AKTIENGESELLSCHAFT (DE) 2007-05-31 US claimed
WO-2007051738-A1 HYDROGEN-CATALYSED PROCESS FOR PREPARING (METH)ACRYLATES OF N-HYDROXY­ALKYLATED LACTAMS BASF SE (DE) 2007-05-10 WO claimed
US-4397750-A ALKENYLSUCCINIC AHYDRIDE DERIVATIVES MOBIL OIL CORPORATION (US) 1983-08-09 US claimed
EP-2121559-B1 CATALYTIC METHOD FOR PRODUCING (METH)ACRYLIC ACID ESTERS OF N-HYDROXYALKYLATED LACTAMS BASF SE (DE) 2015-08-26 EP disclosed
US-3968148-A Copolymers of 1-alkenes and acrylic acid derivatives ROHM AND HAAS COMPANY (US) 1976-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100010236-A1 CATALYTIC PROCESS FOR PREPARING (METH)ACRYLIC ESTERS OF N-HYDROXYALKYLATED LACTAMS COASY, MCCC2, PAM POLB 450/4885KMT2A 863/4885MEN1 698/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.